http://esciencenews.com/articles/2010/05/27/nobel.winner.ties.mental.illness.immune.defect
A Nobel Prize-winning University of Utah geneticist discovered that bone marrow transplants cure mutant mice who pull out their hair compulsively. The study provides the first cause-and-effect link between immune system cells and mental illness, and points toward eventual new psychiatric treatments. "We're showing there is a direct relationship between a psychiatric disorder and the immune system, specifically cells named microglia that are derived from bone marrow" and are found in the brain, says Mario Capecchi, a distinguished professor of human genetics at the University of Utah School of Medicine. "There's been an inference. But nobody has previously made a direct connection between the two."
The findings – published in the Friday, May 28 issue of the journal Cell – should inspire researchers "to think about potential new immune-based therapies for psychiatric disorders," says Capecchi, a 2007 Nobel laureate in physiology or medicine.
Capecchi and colleagues showed that pathological grooming and hair-pulling in mice – a disorder similar to trichotillomania (trick-o-til-o-MAY-nee-ah) in humans – is caused by a mutant Hoxb8 gene that results in defective microglia, which are immune system cells that originate in bone marrow and migrate from blood to the brain. Microglia defend the brain and spinal cord, attacking and engulfing infectious agents.
Mice with pathological grooming appear to groom normally, but do so too often and for too long, leading to hair removal and self-inflicted skin wounds. The disease of pulling out head or body hair is common in humans; studies in seven international communities found trichotillomania affecting 1.9 to 2.5 of every 100 people.
In the key experiment, geneticist Shau-Kwaun Chen, Capecchi and colleagues transplanted bone marrow from normal mice into 10 mice that had a mutant Hoxb8 gene and compulsively pulled out their own chest, stomach and side fur. As the transplant took hold during ensuing months, grooming behavior became normal, four mice recovered completely and the other six showed extensive hair growth and healing of wounds.
"A lot of people are going to find it amazing," says Capecchi. "That's the surprise: bone marrow can correct a behavioral defect."
Nevertheless, "I'm not proposing we should do bone marrow transplants for any psychiatric disorder" in humans, he says. Bone marrow transplants are expensive, and the risks and complications are so severe they generally are used only to treat life-threatening illnesses, including certain cancers and disabling autoimmune diseases such as lupus.
Capecchi says that mice with the mutant gene that causes pathological grooming now can be used to study the surprising connections between the immune system's microglia cells and mental illness – and ultimately to produce new treatments.
"We think it's a very good model for obsessive-compulsive disorder," he says.
The researchers also transplanted bone marrow into normal mice from Hoxb8 mutant, hair-pulling mice. The normal mice started pulling out their hair compulsively. Normal mice transplanted with normal bone marrow kept grooming normally, while mutant mice implanted with mutant bone marrow exhibited severe grooming and self-mutilation. Half died, probably due to difficulty re-establishing mutant bone marrow.
Capecchi and colleagues also proved that reduced sensitivity to pain among mutant Hoxb8 mice is not the cause of the animals' compulsive grooming and hair removal, as some researchers had believed.
Mutant Microglia from Marrow Link Immunity and Mental Disorder
Capecchi says previous studies have linked the immune system and psychiatric disorders, but not in a cause-and-effect manner.
"If you look at people who are depressed, often you find their immune system isn't working normally," Capecchi says. And studies have shown that genes that confer a higher rate of depression, schizophrenia, obsessive-compulsive disorder, bipolar disorder and autism also "have something to do with the immune system," he adds.
The new findings "provide direct evidence for an association between neuropsychiatric diseases and dysfunction of the immune system or of the blood-forming system," says Capecchi.
Hox genes orchestrate embryo development. Hoxb8 is responsible for maintaining "myeloid progenitor cells," including those that give rise to monocytes, which are white blood cells that move from the circulatory system to the brain and become microglia.
It was surprising that the new study identified mutant microglia cells that originate in bone marrow as the cause of compulsive hair-pulling in mice. Researchers expected to find the mutant Hoxb8 in brain nerve cells that control grooming.
It is the first study to suggest "there is a connection between microglia and behavior – and a direct connection," Capecchi says.
Capecchi says nerve cells or neurons represent only about 10 percent of the brain, and the rest is made of various glial cells, including microglia. There are two kinds of microglia in the brain. Sixty percent are "resident" microglia that form in an embryo's brain even before the blood circulation system develops. The second kind of microglia in the brain – 40 percent of the total – originates in bone marrow, and then moves to the brain, circumventing the blood-brain barrier.
The geneticists believed the mutant microglia originated in bone marrow because they did not find them among the resident microglia present in the mouse brain at birth, but instead saw microglia with mutant Hoxb8 first migrate into the mouse brain two days after birth. To identify the cells in the brain with active mutant Hoxb8 genes, the researchers used a method that attached a fluorescent yellow-green label to such cells.
Pathological Grooming is Different than Scratching an Itchy Rump
Capecchi first reported in 2002 that mice with mutant Hoxb8 genes displayed compulsive grooming and pulling out the hair on their chest, stomach and sides. Over the years, some researchers attributed this to reduced pain sensitivity also observed in mutant Hoxb8 mice, apparently due to nerve damage in the spinal cord. The idea was that reduced sensitivity to pain would make mice scratch more in response to an itch. In the new study, the Utah geneticists concluded that compulsive grooming and reduced sensitivity to pain were due to separate malfunctions of the Hoxb8 gene; the bone marrow transplants that cured hair-pulling did not restore the loss of pain sensitivity.
Also, mutating Hoxb8 genes in microglia from bone marrow made the mice groom pathologically but didn't make them insensitive to pain. Mutating Hoxb8 in the spinal cord resulted in reduced sensitivity to pain, but not compulsive grooming.
Finally, in earlier studies of mice insensitive to pain due to mutant Hoxb8, the mice used paws to scratch too much and cause hair loss and wounds on their rumps, near the tail. But mice in the Utah study used their teeth to remove hair on their chest, stomach and sides. They followed a normal head-to-rear grooming pattern, but did it excessively.
To be Determined: How Mutant Microglia Cause Hair-Pulling
How do mutant immune cells from bone marrow cause pathological grooming?
All we know now is that there are 15 percent fewer microglia in the brain when Hoxb8 is mutant, Capecchi says. "In the next wave of experiments, we can ask how microglia affect behavior. We anticipate it has to affect neural circuitry in some way."
He speculates ways mutant microglia might trigger pathological grooming: The microglia could make cytokines that activate or inhibit nerve activity, and thus influence behavior. Because microglia have long extensions that "feel" the synapses that connect nerve cells, they might be involved in controlling nerve-signal transmissions, he says.
For now, "we have no idea which will be right," Capecchi says.
In Capecchi's 2002 study of mice with compulsive grooming, the researchers recorded the number and duration of each mouse's grooming sessions using a video recorder, which was very labor intensive to analyze. So in the new study, the mouse cages were placed on sensitive vibration-detecting platforms capable of distinguishing mouse vibration from different activities such as eating, drinking, grooming, climbing, sitting still, walking and scratching. They tested the method's accuracy by using a video camera to double check what the mice were doing at times.
The result: Mice with the mutant Hoxb8 gene spent about twice as much time grooming as their normal littermates.
The new study was funded by the Howard Hughes Medical Institute and the National Institutes of Health. Capecchi is senior author. The first author is Chen, who recently completed a Ph.D. in human genetics. They conducted the study with human genetics postdoctoral fellows Petr Tvrdik, Erik Peden and Sen Wu; Gerald Spangrude, an internal medicine professor; and Scott Cho, a graduate student in Spangrude's lab.
Capecchi shared the 2007 Nobel Prize in Physiology or Medicine for developing "gene targeting" in mice, a method of knocking genes out of action to see what goes wrong and thus learn each gene's normal function.
Source: University of Utah Health Sciences
I'm a mother of 2 ASD boys: Joshua & Nicholas... They need Stem Cell to recover, do join me!!!
Monday, January 3, 2011
Thimerosal-free childhood vaccines still suspect in autism
http://www.naturalnews.com/030868_vaccines_autism.html
In a recent article in the Chicago Tribune "Link between autism and vaccines discredited," Dr. Cory Franklin makes the definitive claim that vaccines do not cause autism. The study to which his article refers was published in Pediatrics, the online journal of the American Academy of Pediatrics. Researchers reviewed the medical records and interviews with parents of 1000 children exposed to an undisclosed amount of thimerosal, the mercury containing preservative once used in childhood vaccines. Because only 25% of these children had autism while the rest claimed to be neuro-typical, Pediatrics claims thimerosal-containing vaccines and immunoglobulins do not significantly increase the risk of autism. This hardly discredits or proves anything, especially given that the study in question lacks any scientific evidence. Should we believe that vaccines don`t cause autism just because only 250 out of 1000 cherry-picked kids in this study have the disorder?
What`s in a childhood vaccine?
Even if thimerosal is no longer used in childhood vaccines, there still remains antibiotics like gentamicin, strepomycin and neomycin.
These vaccines are live viruses cultured in chick embryos, monkey liver cells and fetal cow serum. Some are cultured in human lung cells and almost all vaccines are cultured with human albumin - the plasma from another person`s blood collected from aborted fetuses. Then there are detergents, disguised with difficult-to-pronounce names and used for paints, household and industrial cleaners and metal working fluids.
Some vaccines also contain monosodium L-glutamate (MSG), an excitotoxin known to cause cancer and linked to brain and neurological damage in autism, ADHD and Parkinson`s Disease - not to mention formaldehyde (a known carcinogen), antifreeze, aluminum, emulsifiers and "other buffers."
This is not information that is readily handed out at your child`s well-baby visits, but you can go to Merck`s website and download the prescribing information for almost all of their vaccines. For example, Merck lists the MMR-II vaccine as "preservative-free" and the ingredients as follows:
Active Ingredient: Weakened virus of measles, mumps and rubella viruses
Inactive Ingredients: sorbitol, sodium phosphate, potassium phosphate, sucrose, sodium chloride, hydrolyzed gelatin, recombinant human albumin, fetal bovine serum, other buffer and media ingredients, neomycin.
Translation as follows:
Active ingredient (the objective): Three live viruses - measles, mumps and rubella cultured in unborn chickens and human lung tissue of an aborted fetus
Inactive ingredient >(what they can`t make the vaccine without): sugar alcohol; detergent; a buffer or cell washer to allow chemical reactions to occur; sugar; salt; protein extracted from boiled bones, connective tissues, organs and some intestines of animals such as cattle, pigs and horses; DNA containing protein from human blood plasma created in the human liver; plasma from fetal cow blood often drawn from a live cow fetus after its mother is slaughtered; other stuff; antibiotics.
Most people, if given this information beforehand, would not willingly inject themselves or their children with such a toxic cocktail. It is not surprising that recent studies focus on thimerosal, an ingredient that supposedly has been removed from this vaccine more than seven years ago.
After reading this lengthy list of additives, the question remains - can the ingredients of vaccines increase your risk of autism? Or allergies, or disease, or any condition for that matter?
The truth is simple: there are real risks associated with vaccines and autism is only one. Everyone should be informed before they vaccinate or not vaccinate themselves or their children - after all, this is America and it is your choice.
SOURCES:
http://articles.chicagotribune.com/...
http://www.aap.org/advocacy/release...
http://www.merck.com/product/vaccin...
In a recent article in the Chicago Tribune "Link between autism and vaccines discredited," Dr. Cory Franklin makes the definitive claim that vaccines do not cause autism. The study to which his article refers was published in Pediatrics, the online journal of the American Academy of Pediatrics. Researchers reviewed the medical records and interviews with parents of 1000 children exposed to an undisclosed amount of thimerosal, the mercury containing preservative once used in childhood vaccines. Because only 25% of these children had autism while the rest claimed to be neuro-typical, Pediatrics claims thimerosal-containing vaccines and immunoglobulins do not significantly increase the risk of autism. This hardly discredits or proves anything, especially given that the study in question lacks any scientific evidence. Should we believe that vaccines don`t cause autism just because only 250 out of 1000 cherry-picked kids in this study have the disorder?
What`s in a childhood vaccine?
Even if thimerosal is no longer used in childhood vaccines, there still remains antibiotics like gentamicin, strepomycin and neomycin.
These vaccines are live viruses cultured in chick embryos, monkey liver cells and fetal cow serum. Some are cultured in human lung cells and almost all vaccines are cultured with human albumin - the plasma from another person`s blood collected from aborted fetuses. Then there are detergents, disguised with difficult-to-pronounce names and used for paints, household and industrial cleaners and metal working fluids.
Some vaccines also contain monosodium L-glutamate (MSG), an excitotoxin known to cause cancer and linked to brain and neurological damage in autism, ADHD and Parkinson`s Disease - not to mention formaldehyde (a known carcinogen), antifreeze, aluminum, emulsifiers and "other buffers."
This is not information that is readily handed out at your child`s well-baby visits, but you can go to Merck`s website and download the prescribing information for almost all of their vaccines. For example, Merck lists the MMR-II vaccine as "preservative-free" and the ingredients as follows:
Active Ingredient: Weakened virus of measles, mumps and rubella viruses
Inactive Ingredients: sorbitol, sodium phosphate, potassium phosphate, sucrose, sodium chloride, hydrolyzed gelatin, recombinant human albumin, fetal bovine serum, other buffer and media ingredients, neomycin.
Translation as follows:
Active ingredient (the objective): Three live viruses - measles, mumps and rubella cultured in unborn chickens and human lung tissue of an aborted fetus
Inactive ingredient >(what they can`t make the vaccine without): sugar alcohol; detergent; a buffer or cell washer to allow chemical reactions to occur; sugar; salt; protein extracted from boiled bones, connective tissues, organs and some intestines of animals such as cattle, pigs and horses; DNA containing protein from human blood plasma created in the human liver; plasma from fetal cow blood often drawn from a live cow fetus after its mother is slaughtered; other stuff; antibiotics.
Most people, if given this information beforehand, would not willingly inject themselves or their children with such a toxic cocktail. It is not surprising that recent studies focus on thimerosal, an ingredient that supposedly has been removed from this vaccine more than seven years ago.
After reading this lengthy list of additives, the question remains - can the ingredients of vaccines increase your risk of autism? Or allergies, or disease, or any condition for that matter?
The truth is simple: there are real risks associated with vaccines and autism is only one. Everyone should be informed before they vaccinate or not vaccinate themselves or their children - after all, this is America and it is your choice.
SOURCES:
http://articles.chicagotribune.com/...
http://www.aap.org/advocacy/release...
http://www.merck.com/product/vaccin...
Labels:
autism,
ingredients,
Thimerosal,
vaccines
Thursday, October 14, 2010
Study Shows Newborns Who Have Jaundice Are More Likely to Be Diagnosed With Autism
http://www.webmd.com/brain/autism/news/20101011/jaundice-in-newborns-may-be-linked-to-autism
Oct. 11, 2010 -- As many as 60% of full-term newborns and 80% of babies born prematurely develop jaundice in their first few days of life. Now new research suggests the condition may be linked to a higher risk for autism.
Babies with jaundice develop yellowish skin due to excess of the chemical bilirubin, which is a byproduct of the breakdown of red blood cells. Most cases resolve within a week or two of birth. But in very rare cases, jaundice can result in brain damage, cerebral palsy, and even death.
The newly reported study included more than 700,000 children in Denmark. About 35,000 were diagnosed with jaundice as newborns.
More Babies With Jaundice Diagnosed With Autism
Babies who developed jaundice were 67% more likely to be diagnosed with autism during early childhood.
The risk was even higher for babies born in the fall and winter. The risk disappeared in babies whose mothers had not given birth before and in babies born in the spring and summer.
The study suggests a link between jaundice and autism, but it is not clear what that link is, study researcher Rikke Damkjaer Maimburg, PhD, of Denmark’s Aarhus University School of Public Health, tells WebMD.
“We can’t say from a study like this one that the association is causal, so parents shouldn’t worry that a child who has jaundice will develop autism,” she says. “It may be some genetic predisposition is associated with the development of jaundice and autism.”
Published today in the online issue of the journal Pediatrics, the study included all children born in Denmark between 1994 and 2004. Almost 36,000 developed jaundice and 532 were later diagnosed with autism spectrum disorder.
Winter Babies Most at Risk
Among children who developed autism, those born in the fall and winter were almost twice as likely to have had jaundice following birth as those born in the spring and summer.
Exposure to sunlight breaks down bilirubin and is considered protective against jaundice. Several studies have also suggested a link between autism and lack of vitamin D, which is known as the sunshine vitamin because the body produces it in response to sun exposure.
“Children born in the winter are also kept indoors more, exposing them to more infections,” Maimburg says. “This might also have an impact on autism risk, although this is just speculation.”
While there is widespread agreement that both genetic and environmental factors influence autism risk, researchers have yet to identify specific environmental risk factors for the disorder.
Earlier research by the Danish researchers also showed the jaundice-autism link, but findings from a California study published in 2005 showed no association.
Alycia Halladay, PhD, who is director of research for the advocacy group Autism Speaks, says parents should not be concerned that their children will develop autism if they had jaundice as newborns.
“This study does not address whether jaundice or elevated bilirubin plays a causal role in autism,” she says.
Autism Speaks is funding a study designed to determine if vitamin D deficiency in newborns is linked to autism.
By Salynn Boyles
WebMD Health News
Reviewed by Laura J. Martin, MD
Oct. 11, 2010 -- As many as 60% of full-term newborns and 80% of babies born prematurely develop jaundice in their first few days of life. Now new research suggests the condition may be linked to a higher risk for autism.
Babies with jaundice develop yellowish skin due to excess of the chemical bilirubin, which is a byproduct of the breakdown of red blood cells. Most cases resolve within a week or two of birth. But in very rare cases, jaundice can result in brain damage, cerebral palsy, and even death.
The newly reported study included more than 700,000 children in Denmark. About 35,000 were diagnosed with jaundice as newborns.
More Babies With Jaundice Diagnosed With Autism
Babies who developed jaundice were 67% more likely to be diagnosed with autism during early childhood.
The risk was even higher for babies born in the fall and winter. The risk disappeared in babies whose mothers had not given birth before and in babies born in the spring and summer.
The study suggests a link between jaundice and autism, but it is not clear what that link is, study researcher Rikke Damkjaer Maimburg, PhD, of Denmark’s Aarhus University School of Public Health, tells WebMD.
“We can’t say from a study like this one that the association is causal, so parents shouldn’t worry that a child who has jaundice will develop autism,” she says. “It may be some genetic predisposition is associated with the development of jaundice and autism.”
Published today in the online issue of the journal Pediatrics, the study included all children born in Denmark between 1994 and 2004. Almost 36,000 developed jaundice and 532 were later diagnosed with autism spectrum disorder.
Winter Babies Most at Risk
Among children who developed autism, those born in the fall and winter were almost twice as likely to have had jaundice following birth as those born in the spring and summer.
Exposure to sunlight breaks down bilirubin and is considered protective against jaundice. Several studies have also suggested a link between autism and lack of vitamin D, which is known as the sunshine vitamin because the body produces it in response to sun exposure.
“Children born in the winter are also kept indoors more, exposing them to more infections,” Maimburg says. “This might also have an impact on autism risk, although this is just speculation.”
While there is widespread agreement that both genetic and environmental factors influence autism risk, researchers have yet to identify specific environmental risk factors for the disorder.
Earlier research by the Danish researchers also showed the jaundice-autism link, but findings from a California study published in 2005 showed no association.
Alycia Halladay, PhD, who is director of research for the advocacy group Autism Speaks, says parents should not be concerned that their children will develop autism if they had jaundice as newborns.
“This study does not address whether jaundice or elevated bilirubin plays a causal role in autism,” she says.
Autism Speaks is funding a study designed to determine if vitamin D deficiency in newborns is linked to autism.
By Salynn Boyles
WebMD Health News
Reviewed by Laura J. Martin, MD
Monday, July 12, 2010
Vaccine ingredients - shocking truth
VACCINE INGREDIENTS
Below is a list of ingredients in vaccines. (It is not exhaustive - there are other chemicals not in the list.)
If you are tempted to assume that these poisons would only be in harmless quantities in vaccines, note:
1) There is no safe level for some of these poisons, such as formaldehyde and mercury, even if one of them was consumed or injected on its own.
2) Even if the quantity of any given ingredient was within a safe level, remember that a large number of these are being taken in all at once, which can lead to the accumulative toxicity being much higher.
3) Poisons such as formaldehyde and mercury are well known to have a sensitising effect on the body, i.e. they cause increased susceptibility to any foreign substance that it might encounter at the same time or in the future.
4) Even the manufacturers admit to a large list of adverse effects of vaccines, including even death.
The resultant damage, including brain damage, from these toxins can vary from mild enough not to be apparent, through to severe, in some cases death. You cannot inject a living being with these poisons and expect there to be no adverse effect at all. What varies, and varies greatly, is merely the degree of damage. The reason for the large variation in this degree of damage include: great genetic variations in recipients, affecting susceptibility in general and susceptibility to specific vaccines variations within one recipient from one time to another (due to biorhythms, other work the immune system is doing already fighting other infections, how many vaccines have already been given, etc), and variations between vaccine batches - there is an acknowledged weakness in the area of controlling the levels of toxins in vaccines, resulting in some batches being labelled "hot lots". (Sadly even this identification does not necessarily result in recalls, but rather in distributing the "hot lot" as broadly as possible, as revealed in a leaked letter from a pharmaceutical company).
Post mortems on cot death babies indicate asphyxia, which can be due to the level of poisons being just that little bit too high for these individuals' immature immune systems to mount a defence of the strength and sustained period of time required to deal with them.
Adding to the difficulty in dealing with the large load of poisons is the fact that these poisons interfere with the activities of the immune system itself, and thus weaken its ability to eliminate any poisons. In the younger babies the battle is more often lost within hours or a few days from the injection. In the older babies they more often hold out longer and only lose the battle after a few weeks or longer (J Pediatrics 1982). For chemical profiles and definitions, visit http://www.scorecard.org/
Sources: EDF (Environmental Defense Fund) & MME (Mosby's Medical Encyclopaedia)
Formaldehyde: (Used in vaccines as a tissue fixative)
Aust. National Research Council: Fewer than 20% but perhaps more than 10% of the general population may be susceptible to formaldehyde and may react acutely at any exposure level. More hazardous than most chemicals in 5 out of 12 ranking systems, on at least 8 federal regulatory lists, ranked as one of the most hazardous compounds (worst 10%) to ecosystems and human health (Environmental Defense Fund).
It is not safe at ANY level.
National Academy of Science:There is no population threshold for irritation effects.
National Research Council:Fewer than 20% but perhaps more than 10% of the general population may be susceptible to formaldehyde and may react acutely at any exposure level.
Formaldehyde is oxidised to formic acid which leads to acidosis and nerve damage. Acidosis can be described as a condition in which the acidity of the body tissues and fluids is abnormally high. The liver and the kidneys may also be damaged.
Other effects: Eye; nasal; throat and pulmonary irritation; acute sense of smell; alters tissue proteins; anaemia; antibodies formation; apathy; blindness; blood in urine; blurred vision; body aches; bronchial spasms; bronchitis; burns nasal and throat; cardiac impairment; palpitations and arrhythmias; central nervous system depression; changes in higher cognitive functions; chemical sensitivity; chest pains and tightness; chronic vaginitis; colds; coma; conjunctivitis; constipation; convulsions; corneal erosion; cough; death; destruction of red blood cells; depression; dermatitis; diarrhoea; difficulty concentrating; disorientation; dizziness; ear aches; eczema; emotional upsets; ethmoid polyps; fatigue; fecula bleeding; foetal asphyxiation (and they don't know what could cause SIDS?); flu-like or cold like illness; frequent urination with pain; gastritis; gastrointestinal inflammation; headaches; haemolytic anaemia; haemolytic haematuria; hoarseness; hyperactive airway disease; hyperactivity; hypomenstrual syndrome; immune system sensitiser; impaired (short) attention span; impaired capacity to attain attention; inability or difficulty swallowing; inability to recall words and names; inconsistent IQ profiles; inflammatory diseases of the reproductive organs; intestinal pain; intrinsic asthma; irritability; jaundice; joint pain; aches and swelling; kidney pain; laryngeal spasm; loss of memory; loss of sense of smell; loss of taste; malaise; menstrual and testicular pain; menstrual irregularities; metallic taste; muscle spasms and cramps; nasal congestions; crusting and mucosae inflammation; nausea; nosebleeds; numbness and tingling of the forearms and finger tips; pale, clammy skin; partial laryngeal paralysis; pneumonia; post nasal drip; pulmonary oedema; reduced body temperature; retarded speech pattern; ringing or tingling in the ear; schizophrenic- type symptoms; sensitivity to sound; shock; short term memory loss; shortness of breath; skin lesions; sneezing; sore throat; spacey feeling; speaking difficulty; sterility; swollen glands; tearing; thirst; tracheitis; tracheobronchitis; vertigo; vomiting blood; vomiting; wheezing.
References; C. Wilson; Chronic Exposure and Human Health (1993), McFarland & Company taken from Our Toxic Times Feb 1997 pgs 18 & 19.
Mercury: (Used in vaccines as a preservative. ) Before you say, "But haven't they removed mercury from the vaccines on the childhood vaccination schedule?" read this: http://www.mercurypoisoned.com/mercury_still_in_vaccines.html
See this video filmed by the University of Calgary of an actual brain neuron - watch what happens to it when it is exposed to (a low amount of) mercury: http://commons.ucalgary.ca/mercury/
The following is a written article about this video: http://unisci.com/stories/20011/0327013.htm
Mercury is the second most poisonous element known to man (next to uranium and its derivatives).
As illustrated in the above video, neurons are observed to disintegrate in its presence. It has also been found to cause changes to chromosomes. The U.S. has known about the potential problems of thimerosal (compound in vaccines that contains mercury) for many years.
The World Health Organization voiced concerns as far back as 1990. Mercury is a highly toxic element which does not easily leave the body. Once ingested, injected, or inhaled, it stays and accumulates. An infant can receive in one day's doses of vaccines as much as the absolute maximum set by the W.H.O. for 3 months of exposure, but it is not safe at ANY level.
Thimerosal is listed as a recognized developmental toxicant as well as a suspected skin or sense organ toxicant by the Environmental Defense Fund1. The following was taken from a website affiliated with the National Institutes for Health2:"Symptoms of exposure to this class of compounds includes aphthous, stomatitis, catarrhal gingivitis, nausea, liquid stools, pain, liver disorder, injury to the cardiovascular system and hematopoietic system, deafness and ataxia. Exposure may be fatal.
Headache, paresthesia of the tongue, lips, fingers and toes, other non-specific dysfunctions, metallic taste, slight gastrointestinal disturbances, excessive flatus and diarrhea may occur. Acute poisoning may cause gastrointestinal irritation and renal failure. Early signs of severe poisoning include fine tremors of extended hands, loss of side vision, slight loss of coordination in the eyes, speech, writing and gait, inability to stand or carry out voluntary movements, occasional muscle atrophy and flexure contractures, generalized myoclonic movements, difficulty understanding ordinary speech, irritability and bad temper progressing to mania, stupor, coma, mental retardation in children, skin irritation, blisters and dermatitis. Other symptoms include chorea, athetosis, tremors, convulsions, pain and numbness in the extremities, nephritis, salivation, loosening of the teeth, blue line on the gums, anxiety, mental depression, insomnia, hallucinations and central nervous system effects. Exposure may also cause irritation of the eyes, mucous membranes and upper respiratory tract."
References:
1.) Environmental Defense Fund - http://www.edf.org/home.cfm
2.) National Institutes for Health - http://health.nih.gov/
Here is an excerpt from "The Vaccine Guide: Making an Informed Choice" (Randall Neustaedter, North Atlantic Books, 1996): "Sensitivities to thimerosal in vaccines apparently develop as a result of previous vaccinations (Förström et al., 1980). Even the minute amount of thimerosal used in vaccines (.1 to .01%) can specifically stimulate the immune system and cause sensitization (Aberer, 1991). Mercury is a violent poison with many toxic effects. The toxicity of mercury varies depending on the form in which the element appears. Metallic mercury has different effects than inorganic or organic mercury compounds. However, major differences in toxicity are not expected among the different compounds within the inorganic group of mercury salts (Clement, 1992)...
...The neurologic toxicity symptoms caused by mercury compounds have a delayed onset after exposure (Bakir et al, 1973), which may have significance for the suspected long-term neurologic symptoms of learning disabilities and behaviour disorders associated with vaccines. (For full references, refer to book.)"
Antifreeze: (This is in the polio vaccine.) Classed as "Very Toxic Material". May lead to kidney, liver, blood and central nervous system (CNS) disorders. Harmful or fatal if swallowed. Effects include behavioural disorders, drowsiness, vomiting, diarrhoea, visual disturbances, thirst, convulsions, cyanosis, and rapid heart rate, CNS stimulation, depression, cardiopulmonary effects, kidney disorders. May also lead to liver and blood disorders. Produces reproductive and developmental effects in experimental animals. (Source: http://www.vetmed.wsu.edu/cliented/antifreeze.aspx)
Aluminium: EDF Suspected - cardiovascular or blood toxicant, neurotoxicant, respiratory toxicant. Implicated as a cause of brain damage; suspected factor in Alzheimer's Disease, dementia, convulsions and comas. More hazardous than most chemicals in 2 out of 6 ranking systems. On at least 2 federal regulatory lists. (This element is not toxic when only in trace amounts, indeed at such levels is even beneficial to the body, however a trace amount is extremely minute - the level in vaccines is enormously higher, at around 0.5%)
2-Phenoxyethanol: - EDF Suspected - developmental toxicant, reproductive toxicant. Metabolic poison (i.e. interferes with the metabolism in all cells). Capable of disabling the immune system's primary response. Contains phenol (see below).
Phenol: EDF Suspected - cardiovascular or blood toxicant aka Carbolic Acid, developmental toxicant, gastrointestinal or liver toxicant, kidney toxicant, neurotoxicant, respiratory toxicant, skin or sense organ toxicant. More hazardous than most chemicals in 3 out of 10 ranking systems. On at least 8 federal regulatory lists
Methanol: Described as a volatile, flammable and poisonous liquid alcohol. In industry, it is used as a solvent and an antifreeze compound in fuel. In the body it is metabolised to formaldehyde (see above). Whilst it can be found naturally in the pectin that ispresent in some common fruits, it is only in very small quantities in fruit and does not pose a danger to the body in that form.
Borax: (sodium tetraborate decahydrate) :Traditionally used as a pesticide, including ant killer. Suspected cardiovascular or blood toxicant, endocrine toxicant, gastrointestinal or liver toxicant and neurological toxicant. Found to cause reproductive damage and reduced fertility in a study on rats.
Glutaraldehyde: Poisonous if ingested (would be worse if injected). Causes birth defects in experimental animals.
MSG:
(monosodium glutamate):In a 1995 report by the Federation of American Societies for Experimental Biology (FASEB) two groups of people were defined as intolerant of MSG - those who eat large quantities of MSG (which is in many processed foods as a flavour enhancer - # 621) and those with "severe, poorly controlled asthma". (Can you guess now why sensitivity to MSG is so common?) According to this report which was contracted by the FDA the following are symptoms that they found in reaction to MSG.
A. Burning sensation in the back of the neck, forearms and chest
B. Numbness in the back of the neck, radiating to the arms and back
C. Tingling, warmth, and weakness in the face, temples, upper back, neck and arms
D. Facial pressure or tightness
E. Chest pain
F. Headache
G. Nausea
H. Rapid heartbeat
I. Bronchospasm (difficulty breathing) in MSG-intolerant people with asthma
J. Drowsiness
K. Weakness
An FDA web page called "FDA and Monosodium Glutamate (MSG)" states "Injections of glutamate in laboratory animals have resulted in damage to nerve cells in the brain."
In 1978 MSG was removed from baby food and other baby products for infants less than one year of age because the American Academy of Pediatrics and the National Academy of Sciences expressed concerns.
Sulfate and phosphate compounds (to one or more of which your child may have already developed a severe allergy from past vaccinations. )
Ammonium Sulfate:EDF Suspected - gastrointestinal or liver toxicant, neurotoxicant, respiratory toxicant.
Gentamicin Sulfate: an antibiotic.
Neomycin Sulfate:an antibiotic. Interferes with Vitamin B6 absorption. An error in the uptake of B6 can cause a rare form of epilepsy and mental retardation.
Tri(n)butylphosphate:EDF Suspected - kidney toxicant, neurotoxicant. More hazardous than most chemicals in 2 out of 3 ranking systems. On at least 1 federal regulatory list.
Polymyxin B: another antibiotic
Polysorbate 20/80: EDF Suspected - skin or sense organ toxicant. Known to cause cancer in animals.
Sorbitol: EDF Suspected - gastrointestinal or liver toxicant. Less hazardous than most chemicals in 1 ranking system.
Polyribosylribitol: a component of the Hib bacterium.
Beta-Propiolactone: EDF Recognized - carcinogen, EDF Suspected - gastrointestinal or liver toxicant, respiratory toxicant, skin or sense organ toxicant. More hazardous than most chemicals in 3 out of 3 ranking systems. On at least 5 federal regulatory lists. Ranked as one of the most hazardous compounds (worst 10%) to humans.
Amphotericin B: MME definition - "a drug used to treat fungus infections. Known allergy to this drug prohibits use. Side effects include blood clots, blood defects, kidney problems, nausea and fever. When used on the skin, allergic reactions can occur."
Animal organ tissue and blood: Animal cell lines need to be used to ulture the viruses in vaccines, so this material is included in the formulation that is injected. Other than when this protein material is digested (i.e. consumed and broken down into its component amino acids, etc, before absorption), it is unusable and toxic to the body. It can also contain many animal viruses (see Animal Viruses).
Animals used include monkey (kidney), cow (heart), calf (serum), chicken (embryo and egg), duck (egg), pig (blood), sheep (blood), dog (kidney), horse (blood), rabbit (brain), guinea pig, etc.
Aborted human foetal tissue and human albumin: This is something you might like to consider if you are against abortion. Also from a health point of view tissue from another human (not just animals) is still foreign and therefore toxic to the body.
Large foreign proteins:In addition to the above accompanying (protein) material, there are large proteins that are deliberately included, used for such purposes as adjuvants (i.e. to help get an immune "response"). Egg album and gelatin (or gelatine, obtained from selected pieces of calf and cattle skins, de-mineralized cattle bones and pork skin) are in several vaccines. Casein (milk protein) is in the triple antigen, i.e. DPT vaccine. As explained above, when injected, proteins are toxic to the body. Hence the immune system "response" - it is stressed by this invasion, which results in sensitisation - it becomes sensitive to these substances, not immune to them.
Is it any wonder, then, that allergies to these substances are now so common (in the case of milk, resulting in the relatively recent emergence of milk alternatives such as soy and rice "milk"s)?
Latex: This is in the hepatitis B vaccine which is given routinely to health workers. Have you heard about the problem of the high occurrence of latex allergy among nurses? How do you think they became sensitised to latex? Allergic reactions can be life-threatening. Hepatitis B vaccine is now routinely given to newborn babies in many countries, including Australia and the US.
Animal Viruses: Some of these can be particularly alien to the human body. The most frequently documented and publicised example is the monkey virus SV40. This is harmless in monkeys, but inject it into a human and it can cause cancer – in the brain (tumours), bone (e.g. multiple myeloma), lungs (mesothelioma) and lymphoid tissue (lymphoma). It has appeared in people born in the last 20 years (The Journal of Infectious Diseases, Sep 1999;180:884- 887), long after the manufacturer claimed to have "cleaned up" the polio vaccine in which it was found. Such cases include the late Alexander Horwin, both of whose parents tested negative for SV40, therefore recent cases cannot just be blamed on inheritance from parents who received the vaccine (see http://www.ouralexander.org/).
Human Viruses: The viruses against which the vaccine is supposed to protect are frequently said to be "killed", "inactivated" or "attenuated" . This is a myth. The main method used to inactivate viruses is treatment with formaldehyde, whose effectiveness is only limited, and even then only temporary - once the brew is injected into the body and disperses, it is documented in orthodox medical literature that these "killed" viruses can revert to their former
virulence. (References for this are available.)
Please note also that whilst the included viruses, bacteria etc against which the vaccine is supposed to protect are claimed to be in "very small doses", the quantities are quite high enough for the diseases to occur, as they can do quite severely, occasionally even leading to death (e.g. deaths reported recently in the Lancet from yellow fever contracted from that vaccine). Indeed a susceptible person can succumb to infection when exposed to only a minute dose (particularly when directly injected), while a sufficiently healthy person will not succumb even when exposed, naturally that is, to an enormous dose. It is not the pathogen, but the interaction between pathogen and host that causes disease to appear (Intervirology 1993).
If the symptoms of a disease do not occur after a vaccine, it cannot be assumed that the person is not or will not be harmed by that pathogen. Most disease symptoms are actually the visible signs of the body's effort to defend itself against the pathogen, and with injections, important defences are bypassed.
Bacteria and the toxins they produce: The human blood is supposed to be, and traditionally was, sterile - no bacteria (or other organisms) present in it. That is not the case any more. Naturally this has a weakening effect on the immune system, apart from
sometimes leading to severe bacterial infections.
Mycoplasma: These are microscopic organisms lacking rigid cell walls and considered to be the smallest free-living organisms. Many are pathogenic and one species is a cause of mycoplasma pneumonia which interestingly is noted to occur "in children and young adults" (Mosby's Medical Dictionary). So, are these only in vaccines by mistake as contaminants? No, believe it or not, they are deliberately included as adjuvants, i.e. to increase the immune system's "response" to the vaccine. http://en.wikipedia.org/wiki/Mycoplasma
Genetically modified yeast: This is in the hepatitis B vaccine.
http://www.novaccine.com/vaccine-ingredients/results.asp?sc=32 Given the controversy over the ingestion of genetically modified foods, how much less safe, do you think, is the injection of them, particularly considering what follows below? http://www.organicconsumers.org/articles/article_3682.cfm
Plus: YEAST = MOLD
Effects of Mold Exposure:
Mold is a type of fungus comprised of microorganisms that seek damp locations to form colonies. Mold spores can be released into the air and inhaled, causing allergies, sinus irritation, respiratory problems (such as asthma), headaches and disorientation. In severe cases, immune system damage can result.
Mold that receives the right nutrients can become toxic, leading to the production of poisonous spores. Specifically, the growth of toxic black mold encourages the formation and release of volatile organic compounds (VOCs) and other serious irritants. Black mold has the potential to cause severe damage to the respiratory, digestive and nervous systems, so it is necessary to take steps for removal immediately. http://www.mold-help.org/content/view/411/
Foreign DNA: This DNA is from such organisms as various animals, animal/human viruses, fungi and bacteria. It has been documented that the injecting foreign DNA can cause it or some of it to be incorporated into the recipient's DNA (see 'Immunisation' Against Diseases for Children). Remember, nature has not experienced such a direct invasion as this before, so can you be sure that it would have developed a way to protect your body against it?
Below is a list of ingredients in vaccines. (It is not exhaustive - there are other chemicals not in the list.)
If you are tempted to assume that these poisons would only be in harmless quantities in vaccines, note:
1) There is no safe level for some of these poisons, such as formaldehyde and mercury, even if one of them was consumed or injected on its own.
2) Even if the quantity of any given ingredient was within a safe level, remember that a large number of these are being taken in all at once, which can lead to the accumulative toxicity being much higher.
3) Poisons such as formaldehyde and mercury are well known to have a sensitising effect on the body, i.e. they cause increased susceptibility to any foreign substance that it might encounter at the same time or in the future.
4) Even the manufacturers admit to a large list of adverse effects of vaccines, including even death.
The resultant damage, including brain damage, from these toxins can vary from mild enough not to be apparent, through to severe, in some cases death. You cannot inject a living being with these poisons and expect there to be no adverse effect at all. What varies, and varies greatly, is merely the degree of damage. The reason for the large variation in this degree of damage include: great genetic variations in recipients, affecting susceptibility in general and susceptibility to specific vaccines variations within one recipient from one time to another (due to biorhythms, other work the immune system is doing already fighting other infections, how many vaccines have already been given, etc), and variations between vaccine batches - there is an acknowledged weakness in the area of controlling the levels of toxins in vaccines, resulting in some batches being labelled "hot lots". (Sadly even this identification does not necessarily result in recalls, but rather in distributing the "hot lot" as broadly as possible, as revealed in a leaked letter from a pharmaceutical company).
Post mortems on cot death babies indicate asphyxia, which can be due to the level of poisons being just that little bit too high for these individuals' immature immune systems to mount a defence of the strength and sustained period of time required to deal with them.
Adding to the difficulty in dealing with the large load of poisons is the fact that these poisons interfere with the activities of the immune system itself, and thus weaken its ability to eliminate any poisons. In the younger babies the battle is more often lost within hours or a few days from the injection. In the older babies they more often hold out longer and only lose the battle after a few weeks or longer (J Pediatrics 1982). For chemical profiles and definitions, visit http://www.scorecard.org/
Sources: EDF (Environmental Defense Fund) & MME (Mosby's Medical Encyclopaedia)
Formaldehyde: (Used in vaccines as a tissue fixative)
Aust. National Research Council: Fewer than 20% but perhaps more than 10% of the general population may be susceptible to formaldehyde and may react acutely at any exposure level. More hazardous than most chemicals in 5 out of 12 ranking systems, on at least 8 federal regulatory lists, ranked as one of the most hazardous compounds (worst 10%) to ecosystems and human health (Environmental Defense Fund).
It is not safe at ANY level.
National Academy of Science:There is no population threshold for irritation effects.
National Research Council:Fewer than 20% but perhaps more than 10% of the general population may be susceptible to formaldehyde and may react acutely at any exposure level.
Formaldehyde is oxidised to formic acid which leads to acidosis and nerve damage. Acidosis can be described as a condition in which the acidity of the body tissues and fluids is abnormally high. The liver and the kidneys may also be damaged.
Other effects: Eye; nasal; throat and pulmonary irritation; acute sense of smell; alters tissue proteins; anaemia; antibodies formation; apathy; blindness; blood in urine; blurred vision; body aches; bronchial spasms; bronchitis; burns nasal and throat; cardiac impairment; palpitations and arrhythmias; central nervous system depression; changes in higher cognitive functions; chemical sensitivity; chest pains and tightness; chronic vaginitis; colds; coma; conjunctivitis; constipation; convulsions; corneal erosion; cough; death; destruction of red blood cells; depression; dermatitis; diarrhoea; difficulty concentrating; disorientation; dizziness; ear aches; eczema; emotional upsets; ethmoid polyps; fatigue; fecula bleeding; foetal asphyxiation (and they don't know what could cause SIDS?); flu-like or cold like illness; frequent urination with pain; gastritis; gastrointestinal inflammation; headaches; haemolytic anaemia; haemolytic haematuria; hoarseness; hyperactive airway disease; hyperactivity; hypomenstrual syndrome; immune system sensitiser; impaired (short) attention span; impaired capacity to attain attention; inability or difficulty swallowing; inability to recall words and names; inconsistent IQ profiles; inflammatory diseases of the reproductive organs; intestinal pain; intrinsic asthma; irritability; jaundice; joint pain; aches and swelling; kidney pain; laryngeal spasm; loss of memory; loss of sense of smell; loss of taste; malaise; menstrual and testicular pain; menstrual irregularities; metallic taste; muscle spasms and cramps; nasal congestions; crusting and mucosae inflammation; nausea; nosebleeds; numbness and tingling of the forearms and finger tips; pale, clammy skin; partial laryngeal paralysis; pneumonia; post nasal drip; pulmonary oedema; reduced body temperature; retarded speech pattern; ringing or tingling in the ear; schizophrenic- type symptoms; sensitivity to sound; shock; short term memory loss; shortness of breath; skin lesions; sneezing; sore throat; spacey feeling; speaking difficulty; sterility; swollen glands; tearing; thirst; tracheitis; tracheobronchitis; vertigo; vomiting blood; vomiting; wheezing.
References; C. Wilson; Chronic Exposure and Human Health (1993), McFarland & Company taken from Our Toxic Times Feb 1997 pgs 18 & 19.
Mercury: (Used in vaccines as a preservative. ) Before you say, "But haven't they removed mercury from the vaccines on the childhood vaccination schedule?" read this: http://www.mercurypoisoned.com/mercury_still_in_vaccines.html
See this video filmed by the University of Calgary of an actual brain neuron - watch what happens to it when it is exposed to (a low amount of) mercury: http://commons.ucalgary.ca/mercury/
The following is a written article about this video: http://unisci.com/stories/20011/0327013.htm
Mercury is the second most poisonous element known to man (next to uranium and its derivatives).
As illustrated in the above video, neurons are observed to disintegrate in its presence. It has also been found to cause changes to chromosomes. The U.S. has known about the potential problems of thimerosal (compound in vaccines that contains mercury) for many years.
The World Health Organization voiced concerns as far back as 1990. Mercury is a highly toxic element which does not easily leave the body. Once ingested, injected, or inhaled, it stays and accumulates. An infant can receive in one day's doses of vaccines as much as the absolute maximum set by the W.H.O. for 3 months of exposure, but it is not safe at ANY level.
Thimerosal is listed as a recognized developmental toxicant as well as a suspected skin or sense organ toxicant by the Environmental Defense Fund1. The following was taken from a website affiliated with the National Institutes for Health2:"Symptoms of exposure to this class of compounds includes aphthous, stomatitis, catarrhal gingivitis, nausea, liquid stools, pain, liver disorder, injury to the cardiovascular system and hematopoietic system, deafness and ataxia. Exposure may be fatal.
Headache, paresthesia of the tongue, lips, fingers and toes, other non-specific dysfunctions, metallic taste, slight gastrointestinal disturbances, excessive flatus and diarrhea may occur. Acute poisoning may cause gastrointestinal irritation and renal failure. Early signs of severe poisoning include fine tremors of extended hands, loss of side vision, slight loss of coordination in the eyes, speech, writing and gait, inability to stand or carry out voluntary movements, occasional muscle atrophy and flexure contractures, generalized myoclonic movements, difficulty understanding ordinary speech, irritability and bad temper progressing to mania, stupor, coma, mental retardation in children, skin irritation, blisters and dermatitis. Other symptoms include chorea, athetosis, tremors, convulsions, pain and numbness in the extremities, nephritis, salivation, loosening of the teeth, blue line on the gums, anxiety, mental depression, insomnia, hallucinations and central nervous system effects. Exposure may also cause irritation of the eyes, mucous membranes and upper respiratory tract."
References:
1.) Environmental Defense Fund - http://www.edf.org/home.cfm
2.) National Institutes for Health - http://health.nih.gov/
Here is an excerpt from "The Vaccine Guide: Making an Informed Choice" (Randall Neustaedter, North Atlantic Books, 1996): "Sensitivities to thimerosal in vaccines apparently develop as a result of previous vaccinations (Förström et al., 1980). Even the minute amount of thimerosal used in vaccines (.1 to .01%) can specifically stimulate the immune system and cause sensitization (Aberer, 1991). Mercury is a violent poison with many toxic effects. The toxicity of mercury varies depending on the form in which the element appears. Metallic mercury has different effects than inorganic or organic mercury compounds. However, major differences in toxicity are not expected among the different compounds within the inorganic group of mercury salts (Clement, 1992)...
...The neurologic toxicity symptoms caused by mercury compounds have a delayed onset after exposure (Bakir et al, 1973), which may have significance for the suspected long-term neurologic symptoms of learning disabilities and behaviour disorders associated with vaccines. (For full references, refer to book.)"
Antifreeze: (This is in the polio vaccine.) Classed as "Very Toxic Material". May lead to kidney, liver, blood and central nervous system (CNS) disorders. Harmful or fatal if swallowed. Effects include behavioural disorders, drowsiness, vomiting, diarrhoea, visual disturbances, thirst, convulsions, cyanosis, and rapid heart rate, CNS stimulation, depression, cardiopulmonary effects, kidney disorders. May also lead to liver and blood disorders. Produces reproductive and developmental effects in experimental animals. (Source: http://www.vetmed.wsu.edu/cliented/antifreeze.aspx)
Aluminium: EDF Suspected - cardiovascular or blood toxicant, neurotoxicant, respiratory toxicant. Implicated as a cause of brain damage; suspected factor in Alzheimer's Disease, dementia, convulsions and comas. More hazardous than most chemicals in 2 out of 6 ranking systems. On at least 2 federal regulatory lists. (This element is not toxic when only in trace amounts, indeed at such levels is even beneficial to the body, however a trace amount is extremely minute - the level in vaccines is enormously higher, at around 0.5%)
2-Phenoxyethanol: - EDF Suspected - developmental toxicant, reproductive toxicant. Metabolic poison (i.e. interferes with the metabolism in all cells). Capable of disabling the immune system's primary response. Contains phenol (see below).
Phenol: EDF Suspected - cardiovascular or blood toxicant aka Carbolic Acid, developmental toxicant, gastrointestinal or liver toxicant, kidney toxicant, neurotoxicant, respiratory toxicant, skin or sense organ toxicant. More hazardous than most chemicals in 3 out of 10 ranking systems. On at least 8 federal regulatory lists
Methanol: Described as a volatile, flammable and poisonous liquid alcohol. In industry, it is used as a solvent and an antifreeze compound in fuel. In the body it is metabolised to formaldehyde (see above). Whilst it can be found naturally in the pectin that ispresent in some common fruits, it is only in very small quantities in fruit and does not pose a danger to the body in that form.
Borax: (sodium tetraborate decahydrate) :Traditionally used as a pesticide, including ant killer. Suspected cardiovascular or blood toxicant, endocrine toxicant, gastrointestinal or liver toxicant and neurological toxicant. Found to cause reproductive damage and reduced fertility in a study on rats.
Glutaraldehyde: Poisonous if ingested (would be worse if injected). Causes birth defects in experimental animals.
MSG:
(monosodium glutamate):In a 1995 report by the Federation of American Societies for Experimental Biology (FASEB) two groups of people were defined as intolerant of MSG - those who eat large quantities of MSG (which is in many processed foods as a flavour enhancer - # 621) and those with "severe, poorly controlled asthma". (Can you guess now why sensitivity to MSG is so common?) According to this report which was contracted by the FDA the following are symptoms that they found in reaction to MSG.
A. Burning sensation in the back of the neck, forearms and chest
B. Numbness in the back of the neck, radiating to the arms and back
C. Tingling, warmth, and weakness in the face, temples, upper back, neck and arms
D. Facial pressure or tightness
E. Chest pain
F. Headache
G. Nausea
H. Rapid heartbeat
I. Bronchospasm (difficulty breathing) in MSG-intolerant people with asthma
J. Drowsiness
K. Weakness
An FDA web page called "FDA and Monosodium Glutamate (MSG)" states "Injections of glutamate in laboratory animals have resulted in damage to nerve cells in the brain."
In 1978 MSG was removed from baby food and other baby products for infants less than one year of age because the American Academy of Pediatrics and the National Academy of Sciences expressed concerns.
Sulfate and phosphate compounds (to one or more of which your child may have already developed a severe allergy from past vaccinations. )
Ammonium Sulfate:EDF Suspected - gastrointestinal or liver toxicant, neurotoxicant, respiratory toxicant.
Gentamicin Sulfate: an antibiotic.
Neomycin Sulfate:an antibiotic. Interferes with Vitamin B6 absorption. An error in the uptake of B6 can cause a rare form of epilepsy and mental retardation.
Tri(n)butylphosphate:EDF Suspected - kidney toxicant, neurotoxicant. More hazardous than most chemicals in 2 out of 3 ranking systems. On at least 1 federal regulatory list.
Polymyxin B: another antibiotic
Polysorbate 20/80: EDF Suspected - skin or sense organ toxicant. Known to cause cancer in animals.
Sorbitol: EDF Suspected - gastrointestinal or liver toxicant. Less hazardous than most chemicals in 1 ranking system.
Polyribosylribitol: a component of the Hib bacterium.
Beta-Propiolactone: EDF Recognized - carcinogen, EDF Suspected - gastrointestinal or liver toxicant, respiratory toxicant, skin or sense organ toxicant. More hazardous than most chemicals in 3 out of 3 ranking systems. On at least 5 federal regulatory lists. Ranked as one of the most hazardous compounds (worst 10%) to humans.
Amphotericin B: MME definition - "a drug used to treat fungus infections. Known allergy to this drug prohibits use. Side effects include blood clots, blood defects, kidney problems, nausea and fever. When used on the skin, allergic reactions can occur."
Animal organ tissue and blood: Animal cell lines need to be used to ulture the viruses in vaccines, so this material is included in the formulation that is injected. Other than when this protein material is digested (i.e. consumed and broken down into its component amino acids, etc, before absorption), it is unusable and toxic to the body. It can also contain many animal viruses (see Animal Viruses).
Animals used include monkey (kidney), cow (heart), calf (serum), chicken (embryo and egg), duck (egg), pig (blood), sheep (blood), dog (kidney), horse (blood), rabbit (brain), guinea pig, etc.
Aborted human foetal tissue and human albumin: This is something you might like to consider if you are against abortion. Also from a health point of view tissue from another human (not just animals) is still foreign and therefore toxic to the body.
Large foreign proteins:In addition to the above accompanying (protein) material, there are large proteins that are deliberately included, used for such purposes as adjuvants (i.e. to help get an immune "response"). Egg album and gelatin (or gelatine, obtained from selected pieces of calf and cattle skins, de-mineralized cattle bones and pork skin) are in several vaccines. Casein (milk protein) is in the triple antigen, i.e. DPT vaccine. As explained above, when injected, proteins are toxic to the body. Hence the immune system "response" - it is stressed by this invasion, which results in sensitisation - it becomes sensitive to these substances, not immune to them.
Is it any wonder, then, that allergies to these substances are now so common (in the case of milk, resulting in the relatively recent emergence of milk alternatives such as soy and rice "milk"s)?
Latex: This is in the hepatitis B vaccine which is given routinely to health workers. Have you heard about the problem of the high occurrence of latex allergy among nurses? How do you think they became sensitised to latex? Allergic reactions can be life-threatening. Hepatitis B vaccine is now routinely given to newborn babies in many countries, including Australia and the US.
Animal Viruses: Some of these can be particularly alien to the human body. The most frequently documented and publicised example is the monkey virus SV40. This is harmless in monkeys, but inject it into a human and it can cause cancer – in the brain (tumours), bone (e.g. multiple myeloma), lungs (mesothelioma) and lymphoid tissue (lymphoma). It has appeared in people born in the last 20 years (The Journal of Infectious Diseases, Sep 1999;180:884- 887), long after the manufacturer claimed to have "cleaned up" the polio vaccine in which it was found. Such cases include the late Alexander Horwin, both of whose parents tested negative for SV40, therefore recent cases cannot just be blamed on inheritance from parents who received the vaccine (see http://www.ouralexander.org/).
Human Viruses: The viruses against which the vaccine is supposed to protect are frequently said to be "killed", "inactivated" or "attenuated" . This is a myth. The main method used to inactivate viruses is treatment with formaldehyde, whose effectiveness is only limited, and even then only temporary - once the brew is injected into the body and disperses, it is documented in orthodox medical literature that these "killed" viruses can revert to their former
virulence. (References for this are available.)
Please note also that whilst the included viruses, bacteria etc against which the vaccine is supposed to protect are claimed to be in "very small doses", the quantities are quite high enough for the diseases to occur, as they can do quite severely, occasionally even leading to death (e.g. deaths reported recently in the Lancet from yellow fever contracted from that vaccine). Indeed a susceptible person can succumb to infection when exposed to only a minute dose (particularly when directly injected), while a sufficiently healthy person will not succumb even when exposed, naturally that is, to an enormous dose. It is not the pathogen, but the interaction between pathogen and host that causes disease to appear (Intervirology 1993).
If the symptoms of a disease do not occur after a vaccine, it cannot be assumed that the person is not or will not be harmed by that pathogen. Most disease symptoms are actually the visible signs of the body's effort to defend itself against the pathogen, and with injections, important defences are bypassed.
Bacteria and the toxins they produce: The human blood is supposed to be, and traditionally was, sterile - no bacteria (or other organisms) present in it. That is not the case any more. Naturally this has a weakening effect on the immune system, apart from
sometimes leading to severe bacterial infections.
Mycoplasma: These are microscopic organisms lacking rigid cell walls and considered to be the smallest free-living organisms. Many are pathogenic and one species is a cause of mycoplasma pneumonia which interestingly is noted to occur "in children and young adults" (Mosby's Medical Dictionary). So, are these only in vaccines by mistake as contaminants? No, believe it or not, they are deliberately included as adjuvants, i.e. to increase the immune system's "response" to the vaccine. http://en.wikipedia.org/wiki/Mycoplasma
Genetically modified yeast: This is in the hepatitis B vaccine.
http://www.novaccine.com/vaccine-ingredients/results.asp?sc=32 Given the controversy over the ingestion of genetically modified foods, how much less safe, do you think, is the injection of them, particularly considering what follows below? http://www.organicconsumers.org/articles/article_3682.cfm
Plus: YEAST = MOLD
Effects of Mold Exposure:
Mold is a type of fungus comprised of microorganisms that seek damp locations to form colonies. Mold spores can be released into the air and inhaled, causing allergies, sinus irritation, respiratory problems (such as asthma), headaches and disorientation. In severe cases, immune system damage can result.
Mold that receives the right nutrients can become toxic, leading to the production of poisonous spores. Specifically, the growth of toxic black mold encourages the formation and release of volatile organic compounds (VOCs) and other serious irritants. Black mold has the potential to cause severe damage to the respiratory, digestive and nervous systems, so it is necessary to take steps for removal immediately. http://www.mold-help.org/content/view/411/
Foreign DNA: This DNA is from such organisms as various animals, animal/human viruses, fungi and bacteria. It has been documented that the injecting foreign DNA can cause it or some of it to be incorporated into the recipient's DNA (see 'Immunisation' Against Diseases for Children). Remember, nature has not experienced such a direct invasion as this before, so can you be sure that it would have developed a way to protect your body against it?
Thursday, September 17, 2009
New Study: Hepatitis B Vaccine Triples the Risk of Autism in Infant Boys
http://www.ageofautism.com/2009/09/david-kirby-new-study-hepatitis-b-vaccine-triples-the-risk-of-autism-in-infant-boys.html
By David Kirby (Click HERE to read and comment on the HuffPo version of this post.)
“The science is largely complete. Ten epidemiological studies have shown MMR vaccine doesn’t cause autism; six have shown thimerosal doesn’t cause autism.”-- Dr. Paul Offit, “Autism’s False Prophets”
“16 studies have shown no causal association between vaccines and autism, and these studies carry weight in the scientific industry.”-- Dr. Nancy Snyderman, NBC Today Show Medical Editor
Conventional wisdom holds that the autism-vaccine question has been “asked and answered,” and that least 16 large, well-constructed epidemiological studies have thoroughly addressed and debunked any hypothesis that childhood vaccination is in any way associated with an increased risk for autism spectrum disorders.
But there are several critical flaws in such an oversimplified generalization, and they are rarely given close examination by public health experts or members of the media.
To begin with, it is unscientific and perilously misleading for anyone to assert that “vaccines and autism” have been studied and that no link has been found. That’s because the 16 or so studies constantly cited by critics of the hypothesis have examined just one vaccine and one vaccine ingredient. And the studies themselves have critical design flaws and limitations.
The current US childhood immunization schedule calls for 28 injections with 11 different vaccines against 15 different diseases by two years of age. Of those 11 vaccines, only the Measles-Mumps-Rubella (MMR) shot has been studied in association with autism, (although a CDC study of an MMR-plus-chickenpox vaccine did show that the risk for febrile seizures in infants was doubled.)
Meanwhile, those 11 vaccines contain scores of ingredients, only one of which, thimerosal, has ever been tested in association with autism.
It is illogical to exonerate all vaccines, all vaccine ingredients, and the total US vaccine program as a whole, based solely on a handful of epidemiological studies of just one vaccine and one vaccine ingredient. It is akin to claiming that every form of animal protein is beneficial to people, when all you have studied is fish.
Now, a new study has shown that giving Hepatitis B vaccine to newborn baby boys more than triples the associated risk of developing an autism spectrum disorder.
An abstract of the study was published in the September, 2009 issue of the respected journal Annals of Epidemiology. In it, Carolyn Gallagher and Melody Goodman of the Graduate Program in Public Health at Stony Brook University Medical Center, NY, wrote that, “Boys who received the hepatitis B vaccine during the first month of life had 2.94 greater odds for ASD compared to later- or unvaccinated boys.” The authors used U.S. probability samples obtained from National Health Interview Survey (NHIS) 1997–2002 datasets.
The conclusion states that: “Findings suggest that U.S. male neonates vaccinated with hepatitis B vaccine had a 3-fold greater risk of ASD; risk was greatest for non-white boys.”
The authors noted that an earlier study by them found that hepatitis B vaccination was associated with receipt of early intervention/special education services (EIS); in probability samples of U.S. children, and that “children with autistic spectrum disorder (ASD) comprise a growing caseload for EIS.”
The author’s new study used a different database than their earlier study (NHIS vs. NHANES) and they found same thing, suggesting a validation of their findings.Critics will point out that this sample was limited to boys born before 1999, so the results are only applicable to that U.S. male birth cohort, and that the study’s cross-sectional design limits inferences on causality. Another weakness is that the autism diagnoses were parent reported.
On the other hand, these results are generalizable to US boys age 3-17 born prior to 1999; vaccination status was confirmed through medical records; and there was controlling for confounders that may be associated with care seeking behaviors. (The P-value equaled 0.032) The full manuscript is currently under review by another journal.
Assuming that the full manuscript is published in a peer-reviewed journal, it will be among the first university-based population studies to suggest an association between a vaccine and an increased risk for autism. And that would be in direct contradiction to all those MMR and thimerosal studies that purportedly found no such link.
Does that mean that Hepatitis B vaccine causes autism? Of course not (though any relative risk above 2.0 is general considered to prove causation in a US court of law).
But there are other studies, both published and greatly anticipated, which might support a hypothesized causal association between HepB vaccine and ASD, at least in boys.Any day now, data culled from CDC's Autism and Developmental Disabilities Monitoring network (ADDM), is expected to be published in the Morbidity and Mortality Weekly Report, and the numbers are expected to put the rate of autism at around 1 in 100, or higher.ADDM researchers examine the education and (when possible) medical records of all eight-year-old children in selected US cities and states. They look only at eight-year-old cohorts to allow time for all diagnoses to be made, reported and counted.So far, ADDM has published data from just two birth cohorts: children born in 1992 (eight-year-olds in 2000) and those born in 1994 (eight-year-olds in 2002). The 1992 cohort revealed an estimated ASD rate of one in 166, or 60-per-10,000. (This has since been revised to 67-per-10,000, or one in 150).But CDC data for the same six ADDM locations showed an increase in ASD from 6.7 for 1992 births to 7.4 for 1994 births. And now the total average number expected to exceed 100-per-10,000 for the 1996 birth cohort, born just two years later. The overarching question, of course, will be, "why?"There are many possible explanations, though a 50% increase in just two years is astonishing, no matter what its cause. One possible answer is the Hepatitis B vaccine, (which also contained 25 micrograms of mercury containing thimerosal up until 2002). Introduced in 1991, it was the first vaccine ever given on a population basis to newborn babies (within the first three hours after delivery) in human history. But according to the CDC's National Immunization Survey, only 8% of infant children received the Hep B vaccine in 1992, when that birth cohort showed an ASD rate of 1-in-150.By 1994, the number of children receiving Hep B vaccine at birth had reached just 27% --and the same cohort showed a 10% ASD increase in locations where both years were measured. But by 1996, Hep B coverage rate had risen to 82%. And that is the cohort whose ASD rate rose to around 100-per-10,000 or more.Correlation, obviously, does not equal causation. But the uptake rate of that particular immunization is at least one environmental factor that did demonstrably change during the period in question. In addition, some recent studies and vaccine court decisions have supported the contention that Hepatitis B vaccine can damage myelin -- the nervous system's main insulating component -- at least in certain genetically susceptible adults and infants. A study published last October in the journal Neurology found that children who received the Hepatitis B vaccine series were 50% more likely to develop "central nervous system inflammatory demyelination" than children who did not receive the vaccine. Most of this increase was due to the Engerix B brand of the vaccine, manufactured by the UK's GlaxoSmithKline. That brand increased the risk of demyelination by 74%, and patients with confirmed multiple sclerosis were nearly three times more likely to develop the disorder. "Hepatitis B vaccination does not generally increase the risk of CNS inflammatory demyelination in childhood," the authors concluded. "However, the Engerix B vaccine appears to increase this risk, particularly for confirmed multiple sclerosis, in the longer term. Our results require confirmation in future studies."Let’s hope that future studies of neonatal HebB administration, demyelinating disorders, and ASD are completed as quickly as possible.
David Kirby is author of Evidence of Harm, a founding contributor to Huffington Post and a contributor to Age of Autism. His next book, Animal Factory: The Looming Threat of Industrial Pig, Dairy, and Poultry Farms to Humans and the Environment will be released within the year and is available now for pre-order at Amazon.
Love, Gabby. :0)
http://stemcellforautism.blogspot.com/
http://www.facebook.com/gabby911
http://twitter.com/stemcell4autism
"I know of nobody who is purely Autistic or purely neurotypical. Even God had some Autistic moments, which is why the planets all spin." ~ Jerry Newport
By David Kirby (Click HERE to read and comment on the HuffPo version of this post.)
“The science is largely complete. Ten epidemiological studies have shown MMR vaccine doesn’t cause autism; six have shown thimerosal doesn’t cause autism.”-- Dr. Paul Offit, “Autism’s False Prophets”
“16 studies have shown no causal association between vaccines and autism, and these studies carry weight in the scientific industry.”-- Dr. Nancy Snyderman, NBC Today Show Medical Editor
Conventional wisdom holds that the autism-vaccine question has been “asked and answered,” and that least 16 large, well-constructed epidemiological studies have thoroughly addressed and debunked any hypothesis that childhood vaccination is in any way associated with an increased risk for autism spectrum disorders.
But there are several critical flaws in such an oversimplified generalization, and they are rarely given close examination by public health experts or members of the media.
To begin with, it is unscientific and perilously misleading for anyone to assert that “vaccines and autism” have been studied and that no link has been found. That’s because the 16 or so studies constantly cited by critics of the hypothesis have examined just one vaccine and one vaccine ingredient. And the studies themselves have critical design flaws and limitations.
The current US childhood immunization schedule calls for 28 injections with 11 different vaccines against 15 different diseases by two years of age. Of those 11 vaccines, only the Measles-Mumps-Rubella (MMR) shot has been studied in association with autism, (although a CDC study of an MMR-plus-chickenpox vaccine did show that the risk for febrile seizures in infants was doubled.)
Meanwhile, those 11 vaccines contain scores of ingredients, only one of which, thimerosal, has ever been tested in association with autism.
It is illogical to exonerate all vaccines, all vaccine ingredients, and the total US vaccine program as a whole, based solely on a handful of epidemiological studies of just one vaccine and one vaccine ingredient. It is akin to claiming that every form of animal protein is beneficial to people, when all you have studied is fish.
Now, a new study has shown that giving Hepatitis B vaccine to newborn baby boys more than triples the associated risk of developing an autism spectrum disorder.
An abstract of the study was published in the September, 2009 issue of the respected journal Annals of Epidemiology. In it, Carolyn Gallagher and Melody Goodman of the Graduate Program in Public Health at Stony Brook University Medical Center, NY, wrote that, “Boys who received the hepatitis B vaccine during the first month of life had 2.94 greater odds for ASD compared to later- or unvaccinated boys.” The authors used U.S. probability samples obtained from National Health Interview Survey (NHIS) 1997–2002 datasets.
The conclusion states that: “Findings suggest that U.S. male neonates vaccinated with hepatitis B vaccine had a 3-fold greater risk of ASD; risk was greatest for non-white boys.”
The authors noted that an earlier study by them found that hepatitis B vaccination was associated with receipt of early intervention/special education services (EIS); in probability samples of U.S. children, and that “children with autistic spectrum disorder (ASD) comprise a growing caseload for EIS.”
The author’s new study used a different database than their earlier study (NHIS vs. NHANES) and they found same thing, suggesting a validation of their findings.Critics will point out that this sample was limited to boys born before 1999, so the results are only applicable to that U.S. male birth cohort, and that the study’s cross-sectional design limits inferences on causality. Another weakness is that the autism diagnoses were parent reported.
On the other hand, these results are generalizable to US boys age 3-17 born prior to 1999; vaccination status was confirmed through medical records; and there was controlling for confounders that may be associated with care seeking behaviors. (The P-value equaled 0.032) The full manuscript is currently under review by another journal.
Assuming that the full manuscript is published in a peer-reviewed journal, it will be among the first university-based population studies to suggest an association between a vaccine and an increased risk for autism. And that would be in direct contradiction to all those MMR and thimerosal studies that purportedly found no such link.
Does that mean that Hepatitis B vaccine causes autism? Of course not (though any relative risk above 2.0 is general considered to prove causation in a US court of law).
But there are other studies, both published and greatly anticipated, which might support a hypothesized causal association between HepB vaccine and ASD, at least in boys.Any day now, data culled from CDC's Autism and Developmental Disabilities Monitoring network (ADDM), is expected to be published in the Morbidity and Mortality Weekly Report, and the numbers are expected to put the rate of autism at around 1 in 100, or higher.ADDM researchers examine the education and (when possible) medical records of all eight-year-old children in selected US cities and states. They look only at eight-year-old cohorts to allow time for all diagnoses to be made, reported and counted.So far, ADDM has published data from just two birth cohorts: children born in 1992 (eight-year-olds in 2000) and those born in 1994 (eight-year-olds in 2002). The 1992 cohort revealed an estimated ASD rate of one in 166, or 60-per-10,000. (This has since been revised to 67-per-10,000, or one in 150).But CDC data for the same six ADDM locations showed an increase in ASD from 6.7 for 1992 births to 7.4 for 1994 births. And now the total average number expected to exceed 100-per-10,000 for the 1996 birth cohort, born just two years later. The overarching question, of course, will be, "why?"There are many possible explanations, though a 50% increase in just two years is astonishing, no matter what its cause. One possible answer is the Hepatitis B vaccine, (which also contained 25 micrograms of mercury containing thimerosal up until 2002). Introduced in 1991, it was the first vaccine ever given on a population basis to newborn babies (within the first three hours after delivery) in human history. But according to the CDC's National Immunization Survey, only 8% of infant children received the Hep B vaccine in 1992, when that birth cohort showed an ASD rate of 1-in-150.By 1994, the number of children receiving Hep B vaccine at birth had reached just 27% --and the same cohort showed a 10% ASD increase in locations where both years were measured. But by 1996, Hep B coverage rate had risen to 82%. And that is the cohort whose ASD rate rose to around 100-per-10,000 or more.Correlation, obviously, does not equal causation. But the uptake rate of that particular immunization is at least one environmental factor that did demonstrably change during the period in question. In addition, some recent studies and vaccine court decisions have supported the contention that Hepatitis B vaccine can damage myelin -- the nervous system's main insulating component -- at least in certain genetically susceptible adults and infants. A study published last October in the journal Neurology found that children who received the Hepatitis B vaccine series were 50% more likely to develop "central nervous system inflammatory demyelination" than children who did not receive the vaccine. Most of this increase was due to the Engerix B brand of the vaccine, manufactured by the UK's GlaxoSmithKline. That brand increased the risk of demyelination by 74%, and patients with confirmed multiple sclerosis were nearly three times more likely to develop the disorder. "Hepatitis B vaccination does not generally increase the risk of CNS inflammatory demyelination in childhood," the authors concluded. "However, the Engerix B vaccine appears to increase this risk, particularly for confirmed multiple sclerosis, in the longer term. Our results require confirmation in future studies."Let’s hope that future studies of neonatal HebB administration, demyelinating disorders, and ASD are completed as quickly as possible.
David Kirby is author of Evidence of Harm, a founding contributor to Huffington Post and a contributor to Age of Autism. His next book, Animal Factory: The Looming Threat of Industrial Pig, Dairy, and Poultry Farms to Humans and the Environment will be released within the year and is available now for pre-order at Amazon.
Love, Gabby. :0)
http://stemcellforautism.blogspot.com/
http://www.facebook.com/gabby911
http://twitter.com/stemcell4autism
"I know of nobody who is purely Autistic or purely neurotypical. Even God had some Autistic moments, which is why the planets all spin." ~ Jerry Newport
Sunday, April 12, 2009
UK Government Caught Lying On Baby Hep B Vax Safety
The British Government has been caught lying in a news report in The Mail on Sunday newspaper yesterday about a proposal to give 8 week old British babies Hepatitis B vaccinations: New vaccination fears over plan to give hepatitis jabs at eight weeks old12th April 2009.
A Department of Health spokesman was quoted claiming:-
The safety of children is always paramount whenever decisions are taken regarding what vaccines are included as part of the child vaccination programme.“
But 8 week old babies are not at risk from Hepatitis B, with the potential exception of babies born to mothers from countries with claimed-to-have high rates of infection. Around 2000 British born infants are already being vaccinated annually in the UK. At risk groups are intravenous “recreational” drug abusers and those who practice unsafe sex - which rules out 8 week old babies.
And Hepatitis B vaccine has been shown in many peer reviewed research papers [including from Harvard University - detailed references at end] to be associated with numerous infant deaths in the USA and Europe, multiple sclerosis and numerous chronic auto-immune disorders. These latter include Guillain-Barre syndrome, lupus, rheumatism, blood disorders and chronic fatigue.
There has been a criminal judicial investigation in France into the adverse effects of this vaccine. France was the first country to introduce universal Hepatitis B vaccination and saw effects which included the first ever seen and harrowing cases of childhood multiple sclerosis in France.
Research also shows that the prevalence of Hepatitis B is low in the UK, consistent with previous estimates and suggesting that many infections were acquired outside the UK. This all suggests Government should concentrate its efforts on effective treatment rather than vaccination of infants against a disease which does not affect them. Proponents of the vaccination claim rates of Hepatitis B infection are “spiralling” but based on “estimates”. Regrettably “estimates” can be “pulled” in one direction or another depending on which direction those responsible for the “estimates” are more interested in seeing them move. And in these circumstances, they can never be justification for vaccinating all babies to protect adult drug abusers and practitioners of unsafe sex.
Additionally, UK and EU authorities have withdrawn marketing licences for 6 Hepatitis vaccines claiming a lack of efficacy and and denying in one case [Hexavac] any association with 6 infant deaths in Germany. The deaths were reported in a 2005 research paper as possibly caused by the vaccine: “Unexplained cases of sudden infant death shortly after hexavalent vaccination.” Zinka B, Rauch E, Buettner A, Rueff F, Penning R. - Vaccine. 2005 May 18.
The most recent vaccine to lose its authorisation was last week when the Medicines Healthcare regulatory Agency withdrew GlaxoSmithKline’s Hepatitis B Energix B vaccine marketing authorisation with Professor Kent Woods, chief executive of the MHRA stating:-
The safety of the vaccine is not in question, but it is suspected to be ineffective.” MHRA recalls GSK’s Hepatitis B vaccine - 07 Apr 2009 - Regulatory Affairs - Hays Pharma News
The other most recent vaccine to lose its European marketing authorisation was Quintanrix [also from GSK] in August last year. The other vaccines are: Infanrix [GSK], Hepacare [Celltech] and Primavax [Aventis Pasteur].
So if ‘The safety of children is always paramount’ why the British Department of Health is even contemplating such a vaccine for 8 week old babies is beyond comprehension.”
But there is worse to come and it shows the UK’s New Labour Government has been irresponsible handing recently from 1st April 2009 legal power to dictate vaccination policy exclusively to the Joint Committee on Vaccination and Immunisation: UK Government Hands Drug Industry Control of Childhood Vaccination. The JCVI regrettably has a demonstrable track-record of recklessness on safety up to and including the present day, as shown in FOI documents: British Government’s Reckless Disregard for Child Health Safety and UK Government Hands Drug Industry Control of Childhood Vaccination.
The DoH statement published in The Mail on Sunday is also untrue because:-
Under the new law The Health Protection (Vaccination) Regulations 2009 which came into effect on 1st April for England only, the Secretary of State has no power on the grounds of safety to refuse to implement or reverse any Joint Committe on Vaccination and Immunisation recommendation
the JCVI expressly has no remit to take safety into account in its decision-making
[that role is supposedly the MHRA's but regrettably they seem to rubber stamp a great deal of what the drug industry come up with - as has been shown time and again and not just with vaccines, but drugs like Seroxat - the "anti-depressant" shown not to work compared to placebo and which causes adolescents to be 3 times more likely to commit suicide]
the only consideration the Secretary of State can take into account in rejecting JCVI recommendations is cost-effectiveness - not safety
contrary to the UK Department of Health claims, no childhood vaccines used on British children have ever been tested according to the gold standard of evidence - randomised placebo controlled clinical trials.
health officials refuse to ensure large scale studies of total health outcomes between vaccinated and unvaccinated individuals are carried out. These should show differences in overall health between these groups and some medical professionals believe this is because the studies would reveal the unvaccinated are healthier overall and high levels of chronic diseases in vaccinated individuals.
there is no clinical benefit to infants from Hepatitis B vaccine but infants are put at risk of the known and unknown adverse effects
this also means doctors and nurses are being expected to behave unethically and possibly criminally - because no caring parent will consent to a vaccine administered to an 8 week old baby on being told there are risks but no benefits
The main reason for the new drive to more and more vaccines - and this is well published in the trade press - is that the drug industry has been changing its business model. The financial markets have known for many years the old model would fail - that of patented “blockbuster” drugs:-
the drug industry have made vaccines the new growth area because they highly lucrative
they are drugs everyone gets - it is the same business model of Bill Gates’ Microsoft - pretty much everyone has to have Windows software - pretty much everyone gets vax’d
and the drug industry has been working hard behind-the-scenes to pursuade everyone - especially legislators - that they are vital when they are not and lobbying for changes in law just like this new law - which was introduced without Parliamentary debate and appears to be unlawful per se: UK Government Hands Drug Industry Control of Childhood Vaccination
Dr Marc Girard, a specialist in the side effects of drugs and commissioned as a medical expert by French courts in the French criminal investigation into the introduction of universal Hepatitis B vaccination in France, suggests that even in high-endemic countries, the risk/benefit ratio of what he describes as “this unusually toxic vaccine” must be carefully re-assessed.
Regarding the health situation in the UK Dr Girard says the conclusion not to vaccinate is obvious. France was the first country to implement universal hepatitis B vaccination in 1994.
Whilst other evidence is embargoed by the French Courts, Dr. Marc Girard has also been able to publish a scientific review of the unembargoed evidence of the vaccine’s hazards (Autoimmun Rev 2005; 4: 96-100). Dr Girard shows that French health authorities suppress studies demonstrating serious risks.
Dr Girard has previously said:
Whilst the risk factors for babies have changed little, there is now impressive evidence that for a preventive measure, hepatitis B vaccine is remarkable for the frequency, variety and severity of complications from its use. The toxicity of this vaccine is so unusual that, even if crucial data are regrettably concealed or covered by Court order, scientific evidence is already far higher than normally needed to justify severe restrictive measures.“
______________________________________
REFERENCES
UK & EU MARKETING AUTHORISATION WITHDRAWALS
MHRA recalls GSK’s Hepatitis B vaccine - 07 Apr 2009 - Regulatory Affairs - Hays Pharma News
Public Statement on Quintanrix (Common name: diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b conjugate vaccine) Withdrawal of the Marketing Authorisation in the European Union - 29/08/08 - EMEA/424484/08
EMEA announces recommendation for suspension of the marketing authorisation for Hexavac - EMEA/297369/2005
EMEA Questions and Answers on the suspension of Hexavac - EMEA/304888/2005
EMEA Withdrawal of the Marketing Authorisation for the Medicinal Product Hepacare (Triple hepatitis B recombinant vaccine)EMEA/32933/02- 20/12/02
Public Statement on Hepacare (Triple hepatitis B recombinant vaccine)17/12/02 - EMEA/32933/02
Withdrawal of the Marketing Authorisation for the Medicinal Product Primavax (Diptheria, Tetanus, and Hepatitis B vaccine) - 04/12/00 - EMEA/H/2681/00
______________________________________
DEATHS, MULTIPLE SCLEROSIS AND OTHER ADVERSE EFFECTS
“Unexplained cases of sudden infant death shortly after hexavalent vaccination.” Zinka B, Rauch E, Buettner A, Rueff F, Penning R. - Vaccine. 2005 May 18
Vaccinations are considered to be the most effective and safe method preventing infectious diseases. Although hexavalent vaccines like Hexavac((R)) and Infanrix Hexa((R)) are assumed to be well tolerated and safe regarding the rate of immunity [Liese JG, Stojanov S, Berut F, Minini P, Harzer E, Jow S, et al. Large scale safety study of a liquid hexavalent vaccine (D-T-acP-IPV-PRP-T-HBs) administered at 2, 4, 6 and 12-14 months of age. Vaccine 2002;20:448-54; Mallet E, Fabre P, Pines E, Salomon H, Staub T, Schodel F, et al. Immunogenicity and safety of a new liquid hexavalent combines vaccine compared with separate administration of reference licensed vaccines in infants. Pediatr Infect Dis J 2000;19:1119-27], it was noticed that several cases of death occurred shortly after the vaccination. We report six cases of sudden infant death that occurred within 48h after hexavalent vaccination. At post-mortal examination, those cases showed unusual findings, especially in the brain and in laboratory tests. Crude calculations of local epidemiology are compatible with an association between hexavalent vaccination and unusual cases of sudden infant death. If confirmed in systematic studies, our findings would have potentially serious clinical implications.
Neonatal Deaths After Hepatitis B Vaccine - The Vaccine Adverse Event Reporting System, 1991-1998 - Arch Pediatr Adolesc Med. 1999;153:1279-1282
Results: Of 1771 neonatal reports, there were 18 deaths in 8 boys and 9 girls (1 patient unclassified). The mean age at vaccination for these 18 cases was 12 days(range, 1-27 days); median time from vaccination to onset of symptoms was 2 days (range, 0-20 days); and median time from symptoms to death was 0 days (range, 0-15 days). The mean birth weight of the neonates (n = 15) was 3034 g (range, 1828-4678 g). The causes of death for the 17 autopsied cases were sudden infant death syndrome for 12, infection for 3, and 1 case each of intracerebral hemorrhage, accidental suffocation, and congenital heart disease. Conclusion: Few neonatal deaths following HepB vaccination have been reported, despite the use of at least 86 million doses of pediatric vaccine given in the United States since 1991. While the limitations of passive surveillance systems do not permit definitive inference, these data suggest that HepB immunization is not causing a clear increase in neonatal deaths.
Recombinant hepatitis B vaccine and the risk of multiple sclerosis
NEUROLOGY 2004;63:838-842
A prospective study
Miguel A. Hernán, MD, DrPH, Susan S. Jick, DSc, Michael J. Olek, DO and Hershel Jick, MD
From the Department of Epidemiology (Dr. Hernán), Harvard School of Public Health, Boston; Boston Collaborative Drug Surveillance Program (Drs. Susan S. Jick and Hershel Jick), Boston University, Lexington, MA; and Department of Neurology (Dr. Olek), College of Medicine, University of California, Irvine.
Background: A potential link between the recombinant hepatitis B vaccine and an increased risk of multiple sclerosis (MS) has been evaluated in several studies, but some of them have substantial methodologic limitations.
Methods: The authors conducted a nested case-control study within the General Practice Research Database (GPRD) in the United Kingdom. The authors identified patients who had a first MS diagnosis recorded in the GPRD between January 1993 and December 2000. Cases were patients with a diagnosis of MS confirmed through examination of medical records, and with at least 3 years of continuous recording in the GPRD before their date of first symptoms (index date). Up to 10 controls per case were randomly selected, matched on age, sex, practice, and date of joining the practice. Information on receipt of immunizations was obtained from the computer records.
Results: The analyses include 163 cases of MS and 1,604 controls. The OR of MS for vaccination within 3 years before the index date compared to no vaccination was 3.1 (95% CI 1.5, 6.3). No increased risk of MS was associated with tetanus and influenza vaccinations.
Conclusions: These findings are consistent with the hypothesis that immunization with the recombinant hepatitis B vaccine is associated with an increased risk of MS, and challenge the idea that the relation between hepatitis B vaccination and risk of MS is well understood.
Received March 31, 2004. Accepted in final form May 8, 2004.
“Multiple sclerosis and hepatitis B vaccination: Adding the credibility of molecular biology to an unusual level of clinical and epidemiological evidence” Comenge Y; Girard M (Med Hypotheses, doi 10.1016/j.mehy.2005.08.012)
“Autoimmune hazards of hepatitis B vaccine” Girard M (Autoimmun Rev 2005; 4:96-100) (Text available in electronic form on request.)
______________________________________
Low Prevalence in The UK of Hepatitis B and Infections acquired abroad
The prevalence of hepatitis B infection in adults in England and Wales - Epidemiology and Infection (1999), 122:133-138 Cambridge University Press
Cost effectiveness analyses of alternative hepatitis B vaccination programmes in England and Wales require a robust estimate of the lifetime risk of carriage. To this end, we report the prevalence of infection in 3781 anonymized individuals aged 15–44 years whose sera were submitted in 1996 to 16 microbiology laboratories in England and Wales. One hundred and forty-six individuals (3·9%) were confirmed as anti HBc positive, including 14 chronic carriers (0·37%). The prevalence of infection and carriage was higher in samples collected in London and increased with age. No increased risk of infection was seen in sera from genito-urinary (GUM) clinics. Only 15 sera positive for hepatitis B were also positive for hepatitis C. Our results confirm the low prevalence of hepatitis B in England and Wales, are consistent with previous estimates of carriage and suggest that many infections were acquired while resident outside the UK. Future prevalence studies should determine the country of birth and other risk factors for each individual in order to confirm these findings. (Accepted September 14 1998)
A Department of Health spokesman was quoted claiming:-
The safety of children is always paramount whenever decisions are taken regarding what vaccines are included as part of the child vaccination programme.“
But 8 week old babies are not at risk from Hepatitis B, with the potential exception of babies born to mothers from countries with claimed-to-have high rates of infection. Around 2000 British born infants are already being vaccinated annually in the UK. At risk groups are intravenous “recreational” drug abusers and those who practice unsafe sex - which rules out 8 week old babies.
And Hepatitis B vaccine has been shown in many peer reviewed research papers [including from Harvard University - detailed references at end] to be associated with numerous infant deaths in the USA and Europe, multiple sclerosis and numerous chronic auto-immune disorders. These latter include Guillain-Barre syndrome, lupus, rheumatism, blood disorders and chronic fatigue.
There has been a criminal judicial investigation in France into the adverse effects of this vaccine. France was the first country to introduce universal Hepatitis B vaccination and saw effects which included the first ever seen and harrowing cases of childhood multiple sclerosis in France.
Research also shows that the prevalence of Hepatitis B is low in the UK, consistent with previous estimates and suggesting that many infections were acquired outside the UK. This all suggests Government should concentrate its efforts on effective treatment rather than vaccination of infants against a disease which does not affect them. Proponents of the vaccination claim rates of Hepatitis B infection are “spiralling” but based on “estimates”. Regrettably “estimates” can be “pulled” in one direction or another depending on which direction those responsible for the “estimates” are more interested in seeing them move. And in these circumstances, they can never be justification for vaccinating all babies to protect adult drug abusers and practitioners of unsafe sex.
Additionally, UK and EU authorities have withdrawn marketing licences for 6 Hepatitis vaccines claiming a lack of efficacy and and denying in one case [Hexavac] any association with 6 infant deaths in Germany. The deaths were reported in a 2005 research paper as possibly caused by the vaccine: “Unexplained cases of sudden infant death shortly after hexavalent vaccination.” Zinka B, Rauch E, Buettner A, Rueff F, Penning R. - Vaccine. 2005 May 18.
The most recent vaccine to lose its authorisation was last week when the Medicines Healthcare regulatory Agency withdrew GlaxoSmithKline’s Hepatitis B Energix B vaccine marketing authorisation with Professor Kent Woods, chief executive of the MHRA stating:-
The safety of the vaccine is not in question, but it is suspected to be ineffective.” MHRA recalls GSK’s Hepatitis B vaccine - 07 Apr 2009 - Regulatory Affairs - Hays Pharma News
The other most recent vaccine to lose its European marketing authorisation was Quintanrix [also from GSK] in August last year. The other vaccines are: Infanrix [GSK], Hepacare [Celltech] and Primavax [Aventis Pasteur].
So if ‘The safety of children is always paramount’ why the British Department of Health is even contemplating such a vaccine for 8 week old babies is beyond comprehension.”
But there is worse to come and it shows the UK’s New Labour Government has been irresponsible handing recently from 1st April 2009 legal power to dictate vaccination policy exclusively to the Joint Committee on Vaccination and Immunisation: UK Government Hands Drug Industry Control of Childhood Vaccination. The JCVI regrettably has a demonstrable track-record of recklessness on safety up to and including the present day, as shown in FOI documents: British Government’s Reckless Disregard for Child Health Safety and UK Government Hands Drug Industry Control of Childhood Vaccination.
The DoH statement published in The Mail on Sunday is also untrue because:-
Under the new law The Health Protection (Vaccination) Regulations 2009 which came into effect on 1st April for England only, the Secretary of State has no power on the grounds of safety to refuse to implement or reverse any Joint Committe on Vaccination and Immunisation recommendation
the JCVI expressly has no remit to take safety into account in its decision-making
[that role is supposedly the MHRA's but regrettably they seem to rubber stamp a great deal of what the drug industry come up with - as has been shown time and again and not just with vaccines, but drugs like Seroxat - the "anti-depressant" shown not to work compared to placebo and which causes adolescents to be 3 times more likely to commit suicide]
the only consideration the Secretary of State can take into account in rejecting JCVI recommendations is cost-effectiveness - not safety
contrary to the UK Department of Health claims, no childhood vaccines used on British children have ever been tested according to the gold standard of evidence - randomised placebo controlled clinical trials.
health officials refuse to ensure large scale studies of total health outcomes between vaccinated and unvaccinated individuals are carried out. These should show differences in overall health between these groups and some medical professionals believe this is because the studies would reveal the unvaccinated are healthier overall and high levels of chronic diseases in vaccinated individuals.
there is no clinical benefit to infants from Hepatitis B vaccine but infants are put at risk of the known and unknown adverse effects
this also means doctors and nurses are being expected to behave unethically and possibly criminally - because no caring parent will consent to a vaccine administered to an 8 week old baby on being told there are risks but no benefits
The main reason for the new drive to more and more vaccines - and this is well published in the trade press - is that the drug industry has been changing its business model. The financial markets have known for many years the old model would fail - that of patented “blockbuster” drugs:-
the drug industry have made vaccines the new growth area because they highly lucrative
they are drugs everyone gets - it is the same business model of Bill Gates’ Microsoft - pretty much everyone has to have Windows software - pretty much everyone gets vax’d
and the drug industry has been working hard behind-the-scenes to pursuade everyone - especially legislators - that they are vital when they are not and lobbying for changes in law just like this new law - which was introduced without Parliamentary debate and appears to be unlawful per se: UK Government Hands Drug Industry Control of Childhood Vaccination
Dr Marc Girard, a specialist in the side effects of drugs and commissioned as a medical expert by French courts in the French criminal investigation into the introduction of universal Hepatitis B vaccination in France, suggests that even in high-endemic countries, the risk/benefit ratio of what he describes as “this unusually toxic vaccine” must be carefully re-assessed.
Regarding the health situation in the UK Dr Girard says the conclusion not to vaccinate is obvious. France was the first country to implement universal hepatitis B vaccination in 1994.
Whilst other evidence is embargoed by the French Courts, Dr. Marc Girard has also been able to publish a scientific review of the unembargoed evidence of the vaccine’s hazards (Autoimmun Rev 2005; 4: 96-100). Dr Girard shows that French health authorities suppress studies demonstrating serious risks.
Dr Girard has previously said:
Whilst the risk factors for babies have changed little, there is now impressive evidence that for a preventive measure, hepatitis B vaccine is remarkable for the frequency, variety and severity of complications from its use. The toxicity of this vaccine is so unusual that, even if crucial data are regrettably concealed or covered by Court order, scientific evidence is already far higher than normally needed to justify severe restrictive measures.“
______________________________________
REFERENCES
UK & EU MARKETING AUTHORISATION WITHDRAWALS
MHRA recalls GSK’s Hepatitis B vaccine - 07 Apr 2009 - Regulatory Affairs - Hays Pharma News
Public Statement on Quintanrix (Common name: diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b conjugate vaccine) Withdrawal of the Marketing Authorisation in the European Union - 29/08/08 - EMEA/424484/08
EMEA announces recommendation for suspension of the marketing authorisation for Hexavac - EMEA/297369/2005
EMEA Questions and Answers on the suspension of Hexavac - EMEA/304888/2005
EMEA Withdrawal of the Marketing Authorisation for the Medicinal Product Hepacare (Triple hepatitis B recombinant vaccine)EMEA/32933/02- 20/12/02
Public Statement on Hepacare (Triple hepatitis B recombinant vaccine)17/12/02 - EMEA/32933/02
Withdrawal of the Marketing Authorisation for the Medicinal Product Primavax (Diptheria, Tetanus, and Hepatitis B vaccine) - 04/12/00 - EMEA/H/2681/00
______________________________________
DEATHS, MULTIPLE SCLEROSIS AND OTHER ADVERSE EFFECTS
“Unexplained cases of sudden infant death shortly after hexavalent vaccination.” Zinka B, Rauch E, Buettner A, Rueff F, Penning R. - Vaccine. 2005 May 18
Vaccinations are considered to be the most effective and safe method preventing infectious diseases. Although hexavalent vaccines like Hexavac((R)) and Infanrix Hexa((R)) are assumed to be well tolerated and safe regarding the rate of immunity [Liese JG, Stojanov S, Berut F, Minini P, Harzer E, Jow S, et al. Large scale safety study of a liquid hexavalent vaccine (D-T-acP-IPV-PRP-T-HBs) administered at 2, 4, 6 and 12-14 months of age. Vaccine 2002;20:448-54; Mallet E, Fabre P, Pines E, Salomon H, Staub T, Schodel F, et al. Immunogenicity and safety of a new liquid hexavalent combines vaccine compared with separate administration of reference licensed vaccines in infants. Pediatr Infect Dis J 2000;19:1119-27], it was noticed that several cases of death occurred shortly after the vaccination. We report six cases of sudden infant death that occurred within 48h after hexavalent vaccination. At post-mortal examination, those cases showed unusual findings, especially in the brain and in laboratory tests. Crude calculations of local epidemiology are compatible with an association between hexavalent vaccination and unusual cases of sudden infant death. If confirmed in systematic studies, our findings would have potentially serious clinical implications.
Neonatal Deaths After Hepatitis B Vaccine - The Vaccine Adverse Event Reporting System, 1991-1998 - Arch Pediatr Adolesc Med. 1999;153:1279-1282
Results: Of 1771 neonatal reports, there were 18 deaths in 8 boys and 9 girls (1 patient unclassified). The mean age at vaccination for these 18 cases was 12 days(range, 1-27 days); median time from vaccination to onset of symptoms was 2 days (range, 0-20 days); and median time from symptoms to death was 0 days (range, 0-15 days). The mean birth weight of the neonates (n = 15) was 3034 g (range, 1828-4678 g). The causes of death for the 17 autopsied cases were sudden infant death syndrome for 12, infection for 3, and 1 case each of intracerebral hemorrhage, accidental suffocation, and congenital heart disease. Conclusion: Few neonatal deaths following HepB vaccination have been reported, despite the use of at least 86 million doses of pediatric vaccine given in the United States since 1991. While the limitations of passive surveillance systems do not permit definitive inference, these data suggest that HepB immunization is not causing a clear increase in neonatal deaths.
Recombinant hepatitis B vaccine and the risk of multiple sclerosis
NEUROLOGY 2004;63:838-842
A prospective study
Miguel A. Hernán, MD, DrPH, Susan S. Jick, DSc, Michael J. Olek, DO and Hershel Jick, MD
From the Department of Epidemiology (Dr. Hernán), Harvard School of Public Health, Boston; Boston Collaborative Drug Surveillance Program (Drs. Susan S. Jick and Hershel Jick), Boston University, Lexington, MA; and Department of Neurology (Dr. Olek), College of Medicine, University of California, Irvine.
Background: A potential link between the recombinant hepatitis B vaccine and an increased risk of multiple sclerosis (MS) has been evaluated in several studies, but some of them have substantial methodologic limitations.
Methods: The authors conducted a nested case-control study within the General Practice Research Database (GPRD) in the United Kingdom. The authors identified patients who had a first MS diagnosis recorded in the GPRD between January 1993 and December 2000. Cases were patients with a diagnosis of MS confirmed through examination of medical records, and with at least 3 years of continuous recording in the GPRD before their date of first symptoms (index date). Up to 10 controls per case were randomly selected, matched on age, sex, practice, and date of joining the practice. Information on receipt of immunizations was obtained from the computer records.
Results: The analyses include 163 cases of MS and 1,604 controls. The OR of MS for vaccination within 3 years before the index date compared to no vaccination was 3.1 (95% CI 1.5, 6.3). No increased risk of MS was associated with tetanus and influenza vaccinations.
Conclusions: These findings are consistent with the hypothesis that immunization with the recombinant hepatitis B vaccine is associated with an increased risk of MS, and challenge the idea that the relation between hepatitis B vaccination and risk of MS is well understood.
Received March 31, 2004. Accepted in final form May 8, 2004.
“Multiple sclerosis and hepatitis B vaccination: Adding the credibility of molecular biology to an unusual level of clinical and epidemiological evidence” Comenge Y; Girard M (Med Hypotheses, doi 10.1016/j.mehy.2005.08.012)
“Autoimmune hazards of hepatitis B vaccine” Girard M (Autoimmun Rev 2005; 4:96-100) (Text available in electronic form on request.)
______________________________________
Low Prevalence in The UK of Hepatitis B and Infections acquired abroad
The prevalence of hepatitis B infection in adults in England and Wales - Epidemiology and Infection (1999), 122:133-138 Cambridge University Press
Cost effectiveness analyses of alternative hepatitis B vaccination programmes in England and Wales require a robust estimate of the lifetime risk of carriage. To this end, we report the prevalence of infection in 3781 anonymized individuals aged 15–44 years whose sera were submitted in 1996 to 16 microbiology laboratories in England and Wales. One hundred and forty-six individuals (3·9%) were confirmed as anti HBc positive, including 14 chronic carriers (0·37%). The prevalence of infection and carriage was higher in samples collected in London and increased with age. No increased risk of infection was seen in sera from genito-urinary (GUM) clinics. Only 15 sera positive for hepatitis B were also positive for hepatitis C. Our results confirm the low prevalence of hepatitis B in England and Wales, are consistent with previous estimates of carriage and suggest that many infections were acquired while resident outside the UK. Future prevalence studies should determine the country of birth and other risk factors for each individual in order to confirm these findings. (Accepted September 14 1998)
Monday, October 27, 2008
Hepatitis B Shot/High Bilirubin/ ASD CONNECTION
http://www.labtests%20online.org/%20understanding/%20analytes/%20bilirubin/%20test.html
Also known as: Total bilirubin, TBIL, Neonatal bilirubin, Direct bilirubin (conjugated bilirubin), Indirect bilirubin (unconjugated bilirubin) Formal name: Bilirubin Related tests: Liver panel, Gamma-glutamyl transferase, Alkaline phosphatase, Aspartate aminotransferase, Alanine aminotransferase, Hepatitis A, Hepatitis B, Hepatitis C
The Test
How is it used?When is it ordered?What does the test result mean?Is there anything else I should know?
How is it used?
When bilirubin levels are high, a condition called jaundice occurs, and further testing is needed to determine the cause. Too much bilirubin may mean that too much is being produced (usually due to increased hemolysis) or that the liver is incapable of adequately removing bilirubin in a timely manner due to blockage of bile ducts, liver diseases such as cirrhosis, acute hepatitis, or inherited problems with bilirubin processing.
It is not uncommon to see high bilirubin levels in newborns, typically 1 to 3 days old. This is sometimes called physiologic jaundice of the newborn. Within the first 24 hours of life, up to 50% of full-term newborns, and an even greater percentage of pre-term babies, may have a high bilirubin level. After birth, newborns begin breaking down the excess red blood cells (RBCs) they are born with and, since the newborn’s liver is not fully mature, it is unable to process the extra bilirubin, causing the infant's bilirubin levels to rise in the blood and other body tissues. This situation usually resolves itself within a few days. In other instances, newborns’ red blood cells may be being destroyed because of blood incompatibilities between the baby and her mother, called hemolytic disease of the newborn.
In adults or older children, bilirubin is measured to diagnose and/or monitor liver diseases, such as cirrhosis, hepatitis, or gallstones. Patients with sickle cell disease or other causes of hemolytic anemia may have episodes where excessive RBC destruction takes place, increasing bilirubin levels.
When is it ordered?
A doctor usually orders a bilirubin test in conjunction with other laboratory tests (alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase) for a patient who shows signs of abnormal liver function. A bilirubin level may be ordered when a patient:
shows evidence of jaundice has a history of drinking excessive amounts of alcohol has suspected drug toxicity has been exposed to hepatitis viruses
Other symptoms that may be present include:dark, amber-colored urine nausea/vomiting abdominal pain and/or swelling fatigue and general malaise that often accompany chronic liver disease
Determining a bilirubin level in newborns with jaundice is considered standard medical care.
What does the test result mean?NOTE: A standard reference range is not available for this test. Because reference values are dependent on many factors, including patient age, gender, sample population, and test method, numeric test results have different meanings in different labs. Your lab report should include the specific reference range for your test. Lab Tests Online strongly recommends that you discuss your test results with your doctor. For more information on reference ranges, please read
Reference Ranges and What They Mean.
Newborns: Excessive bilirubin damages developing brain cells in infants (kernicterus) and may cause mental retardation, learning and developmental disabilities, hearing loss, or eye movement problems. It is important that bilirubin in newborns does not get too high. When the level of bilirubin is above a critical threshold, special treatments are initiated to lower it. An excessive bilirubin level may result from the accelerated breakdown of red blood cells due to a blood type incompatibility between the mother and her newborn (e.g., the mother is Rh-negative and has antibody to Rh-positive blood - the father is Rh-positive, and the fetus inherits this trait from him; the mother’s antibody crosses the placenta and causes the fetal Rh-positive red blood cells to hemolyze, resulting in excessively elevated bilirubin levels with jaundice, anemia, and possible kernicterus. )
Adults and children: Bilirubin levels can be used to identify liver damage/disease or to monitor the progression of jaundice. Increased total or unconjugated bilirubin may be a result of hemolytic, sickle cell or pernicious anemias or a transfusion reaction. If conjugated bilirubin is elevated, there may be some kind of blockage of the liver or bile ducts, hepatitis, trauma to the liver, cirrhosis, a drug reaction, or long-term alcohol abuse.
Inherited disorders that cause abnormal bilirubin metabolism (Gilbert’s, Rotor’s, Dubin-Johnson, Crigler-Najjar syndromes) may also cause increased levels
.
Low levels of bilirubin are not generally a concern and are not monitored.
Is there anything else I should know?
Although bilirubin may be toxic to brain development in newborns (up to the age of about 2–4 weeks), high bilirubin in older children and adults does not pose the same threat. In older children and adults, the “blood-brain barrier” is more developed and prevents bilirubin from crossing this barrier to the brain cells. Elevated bilirubin levels in children or adults, however, strongly suggest a medical condition that must be evaluated and treated.
Bilirubin is not normally present in the urine. However, conjugated bilirubin is water-soluble and therefore may be excreted from the body in the urine when levels increase in the body. Its presence in the urine usually indicates blockage of liver or bile ducts, hepatitis or some other liver damage. The most common method for detecting urine bilirubin is using the dipstick test that is part of a urinalysis.
Bilirubin levels tend to be slightly higher in males than females, while African Americans show lower values. Strenuous exercise may also increase bilirubin levels.
Engerix hep B vaccine may raise risk of MS in kids:
http://www.nlm.nih.gov/medlineplus/news/fullstory_69759.html
Hepatitis B Vaccine & Adverse Reactions: http://www.umm.%20edu/altmed/%20drugs/hepatitis-%20b-061000.%20htm
Multiple sclerosis reported following administration of hepatitis B and other vaccines: http://us.gsk.com/products/assets/us_engerixb.pdf
Disturbing facts:
- Bilirubin levels tend to be slightly higher in males than females (just like ASD)
- Newborns: Excessive bilirubin damages developing brain cells in infants (kernicterus) and may cause mental retardation, learning and developmental disabilities, hearing loss, or eye movement problems. It is important that bilirubin in newborns does not get too high.
- Reasonst to test an infant are:If they have been exposed to hepatitis viruses (vaccine:Hep B at second day of birth in the hospiital)
- shows evidence of jaundice
- last but not least there is a well documented connection between Hep B vaccine and MS in children.
All this symptoms and facts were present after my son received Hep B vaccine prior to leaving the hospital... One thing it does not mention is the nonstop crying (his voice went horse before we even left the hospital...) He was eating and sleeping fine prior to the shot and developed intolerance to protein after that... and just told me he was a coliky baby and dismissed any observation I had... And told me to go home and put my boy in the sun as much as posible... they never tested levels of bilirubin at all... I could tell he was in a very intence pain and kept on giving Tylenol (which depletes glutathione levels) prescribed by the Pediatrician, probably making things worse!!!
I wish I knew then what I know now...And each time he received a new vaccine he kept having rashes and what not... until 1 year of age when he received MMR and a Flu shot all in one day... after that he went off the deep end and regressed more and more!!! Having very low muscle tone, difficulty with fine motor skills, Sleep depravation, difficulty digesting certain proteins, bloating, pain, and fatigue (this are all symptoms of my child having liver and brain damage). That Hep B shot was the first step we took & started our journey in to ASD world...
And if you add to this the Mercury, Aluminum as well as other aditives in the shots, which have been recently discussed in the theory of vaccines causing micro-vascular stokes from Dr. Moulden... It just makes more sense ... Our children have been injured... vaccine by vaccine and all of them contribute to more and more regressions!!! MMR is just the tip of the iceberg & the straw that broke the camel's back...
With love and concern for the safety of our children, Gabby. :0)
Also known as: Total bilirubin, TBIL, Neonatal bilirubin, Direct bilirubin (conjugated bilirubin), Indirect bilirubin (unconjugated bilirubin) Formal name: Bilirubin Related tests: Liver panel, Gamma-glutamyl transferase, Alkaline phosphatase, Aspartate aminotransferase, Alanine aminotransferase, Hepatitis A, Hepatitis B, Hepatitis C
The Test
How is it used?When is it ordered?What does the test result mean?Is there anything else I should know?
How is it used?
When bilirubin levels are high, a condition called jaundice occurs, and further testing is needed to determine the cause. Too much bilirubin may mean that too much is being produced (usually due to increased hemolysis) or that the liver is incapable of adequately removing bilirubin in a timely manner due to blockage of bile ducts, liver diseases such as cirrhosis, acute hepatitis, or inherited problems with bilirubin processing.
It is not uncommon to see high bilirubin levels in newborns, typically 1 to 3 days old. This is sometimes called physiologic jaundice of the newborn. Within the first 24 hours of life, up to 50% of full-term newborns, and an even greater percentage of pre-term babies, may have a high bilirubin level. After birth, newborns begin breaking down the excess red blood cells (RBCs) they are born with and, since the newborn’s liver is not fully mature, it is unable to process the extra bilirubin, causing the infant's bilirubin levels to rise in the blood and other body tissues. This situation usually resolves itself within a few days. In other instances, newborns’ red blood cells may be being destroyed because of blood incompatibilities between the baby and her mother, called hemolytic disease of the newborn.
In adults or older children, bilirubin is measured to diagnose and/or monitor liver diseases, such as cirrhosis, hepatitis, or gallstones. Patients with sickle cell disease or other causes of hemolytic anemia may have episodes where excessive RBC destruction takes place, increasing bilirubin levels.
When is it ordered?
A doctor usually orders a bilirubin test in conjunction with other laboratory tests (alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase) for a patient who shows signs of abnormal liver function. A bilirubin level may be ordered when a patient:
shows evidence of jaundice has a history of drinking excessive amounts of alcohol has suspected drug toxicity has been exposed to hepatitis viruses
Other symptoms that may be present include:dark, amber-colored urine nausea/vomiting abdominal pain and/or swelling fatigue and general malaise that often accompany chronic liver disease
Determining a bilirubin level in newborns with jaundice is considered standard medical care.
What does the test result mean?NOTE: A standard reference range is not available for this test. Because reference values are dependent on many factors, including patient age, gender, sample population, and test method, numeric test results have different meanings in different labs. Your lab report should include the specific reference range for your test. Lab Tests Online strongly recommends that you discuss your test results with your doctor. For more information on reference ranges, please read
Reference Ranges and What They Mean.
Newborns: Excessive bilirubin damages developing brain cells in infants (kernicterus) and may cause mental retardation, learning and developmental disabilities, hearing loss, or eye movement problems. It is important that bilirubin in newborns does not get too high. When the level of bilirubin is above a critical threshold, special treatments are initiated to lower it. An excessive bilirubin level may result from the accelerated breakdown of red blood cells due to a blood type incompatibility between the mother and her newborn (e.g., the mother is Rh-negative and has antibody to Rh-positive blood - the father is Rh-positive, and the fetus inherits this trait from him; the mother’s antibody crosses the placenta and causes the fetal Rh-positive red blood cells to hemolyze, resulting in excessively elevated bilirubin levels with jaundice, anemia, and possible kernicterus. )
Adults and children: Bilirubin levels can be used to identify liver damage/disease or to monitor the progression of jaundice. Increased total or unconjugated bilirubin may be a result of hemolytic, sickle cell or pernicious anemias or a transfusion reaction. If conjugated bilirubin is elevated, there may be some kind of blockage of the liver or bile ducts, hepatitis, trauma to the liver, cirrhosis, a drug reaction, or long-term alcohol abuse.
Inherited disorders that cause abnormal bilirubin metabolism (Gilbert’s, Rotor’s, Dubin-Johnson, Crigler-Najjar syndromes) may also cause increased levels
.
Low levels of bilirubin are not generally a concern and are not monitored.
Is there anything else I should know?
Although bilirubin may be toxic to brain development in newborns (up to the age of about 2–4 weeks), high bilirubin in older children and adults does not pose the same threat. In older children and adults, the “blood-brain barrier” is more developed and prevents bilirubin from crossing this barrier to the brain cells. Elevated bilirubin levels in children or adults, however, strongly suggest a medical condition that must be evaluated and treated.
Bilirubin is not normally present in the urine. However, conjugated bilirubin is water-soluble and therefore may be excreted from the body in the urine when levels increase in the body. Its presence in the urine usually indicates blockage of liver or bile ducts, hepatitis or some other liver damage. The most common method for detecting urine bilirubin is using the dipstick test that is part of a urinalysis.
Bilirubin levels tend to be slightly higher in males than females, while African Americans show lower values. Strenuous exercise may also increase bilirubin levels.
Researchers find aggressive phototherapy can improve neurodevelopmental outcomes in some preemies:
http://www.cnsfoundation.org/site/News2?news_iv_ctrl=-1&page=NewsArticle&id=8235&autologin=true
Engerix hep B vaccine may raise risk of MS in kids:
http://www.nlm.nih.gov/medlineplus/news/fullstory_69759.html
Hepatitis B Vaccine & Adverse Reactions: http://www.umm.%20edu/altmed/%20drugs/hepatitis-%20b-061000.%20htm
Multiple sclerosis reported following administration of hepatitis B and other vaccines: http://us.gsk.com/products/assets/us_engerixb.pdf
Disturbing facts:
- Bilirubin levels tend to be slightly higher in males than females (just like ASD)
- Newborns: Excessive bilirubin damages developing brain cells in infants (kernicterus) and may cause mental retardation, learning and developmental disabilities, hearing loss, or eye movement problems. It is important that bilirubin in newborns does not get too high.
- Reasonst to test an infant are:If they have been exposed to hepatitis viruses (vaccine:Hep B at second day of birth in the hospiital)
- shows evidence of jaundice
- last but not least there is a well documented connection between Hep B vaccine and MS in children.
All this symptoms and facts were present after my son received Hep B vaccine prior to leaving the hospital... One thing it does not mention is the nonstop crying (his voice went horse before we even left the hospital...) He was eating and sleeping fine prior to the shot and developed intolerance to protein after that... and just told me he was a coliky baby and dismissed any observation I had... And told me to go home and put my boy in the sun as much as posible... they never tested levels of bilirubin at all... I could tell he was in a very intence pain and kept on giving Tylenol (which depletes glutathione levels) prescribed by the Pediatrician, probably making things worse!!!
I wish I knew then what I know now...And each time he received a new vaccine he kept having rashes and what not... until 1 year of age when he received MMR and a Flu shot all in one day... after that he went off the deep end and regressed more and more!!! Having very low muscle tone, difficulty with fine motor skills, Sleep depravation, difficulty digesting certain proteins, bloating, pain, and fatigue (this are all symptoms of my child having liver and brain damage). That Hep B shot was the first step we took & started our journey in to ASD world...
And if you add to this the Mercury, Aluminum as well as other aditives in the shots, which have been recently discussed in the theory of vaccines causing micro-vascular stokes from Dr. Moulden... It just makes more sense ... Our children have been injured... vaccine by vaccine and all of them contribute to more and more regressions!!! MMR is just the tip of the iceberg & the straw that broke the camel's back...
With love and concern for the safety of our children, Gabby. :0)
Subscribe to:
Posts (Atom)
